Diprate

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Diprate Information

Diprate is a prescription drug, available for use as Tablet. Primarily, it is used for the treatment of Epilepsy, Migraine. Diprate also has some secondary and off-label uses. These are listed below.

The optimal dosage of Diprate is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Diprate as well, which are listed below. Such side effects of Diprate normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Diprate is Severe for pregnant women and Mild for women who are breastfeeding. In addition, Diprate's effects on the liver, heart and kidney are discussed below in the Diprate related warnings section.

Diprate is contraindicated in people with pre-existing medical conditions like Depression, Liver Disease as it can result in adverse effects. Some other conditions that can be affected by Diprate are listed in the contraindications section below.

Besides this, Diprate may also have severe interaction with some medicines. A complete list of these interactions is given below.

You should also be aware that Diprate is not safe while driving, and is not addiction.



Diprate Benefits & Uses

Diprate is used to treat the following -

Main Benefits

Other Benefits

Diprate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled.
13 - 18 years (Adolescent)
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled
Geriatric
  • Disease: Mania
  • Before or After Meal: After Meal
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: delayed-release tablet

Diprate Related Warnings

  • Is the use of Diprate safe for pregnant women?


    Diprate shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Diprate safe during breastfeeding?


    Diprate may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Diprate on the Kidneys?


    Diprate may have mild side effects on the kidneys.

    Mild
  • What is the effect of Diprate on the Liver?


    Diprate may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Diprate on the Heart?


    Diprate is not harmful for the heart.

    Safe


Severe Interaction of Diprate with Other Drugs

Diprate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Diprate Contraindications

If you are suffering from any of the following diseases, you should not take Diprate unless your doctor advises you to do so -



Frequently asked Questions about Diprate

  • Is this Diprate habit forming or addictive?


    Forming a habit of Diprate has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Diprate as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, Diprate is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, Diprate is useful in treating mental disorders.

    Yes

Diprate Interactions with Food and Alcohol

  • Interaction between Food and Diprate


    Taking Diprate with food does not harm your health.

    Safe
  • Interaction between Alcohol and Diprate


    Taking alcohol with Diprate can be dangerous.

    Severe


Frequently asked Questions about Diprate

Question over 5 years ago

How to take Diprate?

Dr. Yogesh Kumar MBBS , General Physician

Ideally, Diprate can be taken once or twice daily depends on the severity of disease or advice by the doctor. It has to be taken with food to avoid stomach upset. However, you are recommended to take it as per the doctor's instructions only.

Question about 5 years ago

Can I take Diprate with Paracetamol?

Dr. Saikat Mukherjee MBBS , General Physician

Yes, you can take Diprate with paracetamol (acetaminophen). No harmful interactions exist between them. However, if you feel any discomfort after taking these two drugs together then do not hesitate to discuss it with your doctor.

Question about 5 years ago

Can I discontinue Diprate on my own without doctors advice?

Dr. Kapil Sharma MBBS , General Physician

No. Diprate Should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine own your own can cause unintended side effects.

Question almost 5 years ago

Does Diprate cause erectile dysfunction?

Dr. Bharat MBBS , General Physician

Yes, Diprate causes erectile dysfunction. If you experience erectile dysfunction after taking this drug then do not stop the drug without consulting your doctor. Discuss it with your doctor, he/she will provide you with solutions or prescribe alternative medicines.

Question over 5 years ago

How does Diprate work?

Dr. Manoj Meena MBBS , General Physician

Diprate works by relaxing the muscles of the body and suppressing abnormal activity of nerve cells in the brain through an increase in activity of a chemical messenger known as GABA (gamma-aminobutyric acid) by inhibiting the enzymes which are responsible for its decreased concentration of GABA in the brain. In this way Diprate provides Thus, relief from the seizure and mania associated with bipolar disorder.



See all substitutes for Diprate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 418

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote (divalproex sodium)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote Er (divalproex sodium)



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