Divigel

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1 gm Gel in 1 Tube Out of Stock
₹ 615
1 GM GEL 1 Tube ₹ 615
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  • Manufactured by:
  • Contains / Salt: Estradiol (0.1 %)
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Divigel Information

Divigel is a prescription drug, available for use as Gel. It is typically used for the treatment of Post Menopausal Osteoporosis, Urethritis, Vaginal atrophy. The alternative uses of Divigel have also been explained below.

The optimal dosage of Divigel is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

Common side effects of Divigel include Weight gain, Metrorrhagia, Edema. Apart from the aforementioned side effects, Divigel can also lead to other problems, which have been listed below. Such side effects of Divigel normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Divigel's effect during pregnancy is Severe and Severe while nursing. Further, the section on Divigel related warnings talks about Divigel's effects on the liver, heart and kidney.

Divigel can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Divigel in conditions like High Blood Pressure, Blood Clotting Disorders, Thrombophlebitis. The section on Divigel contraindications lists all such conditions.

Drug interactions for Divigel have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Divigel, it is important to know that it is safe while driving, and is habit-forming.



Divigel Benefits & Uses

Divigel is used to treat the following -

Other Benefits

Divigel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult(Female)
  • Disease: Urethritis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Gel
  • Dosage Route: Topical
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Urethritis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Gel
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Divigel Side Effects

Based on research, the following side effects have been observed when Divigel is used -

Moderate

  • Fluid retention
  • Endometrial Hyperplasia

Mild

  • Headache
  • Nausea or vomiting
  • पेट दर्द
  • Back Pain
  • Diarrhoea
  • Skin irritation
  • Breast pain

Common

  • Weight gain
  • Metrorrhagia
  • Edema

Divigel Related Warnings

  • Is the use of Divigel safe for pregnant women?


    Divigel should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Divigel safe during breastfeeding?


    Taking Divigel may lead to serious side effects if you are breastfeeding. Divigel should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Divigel on the Kidneys?


    There can be some harmful effects on your kidneys after taking Divigel. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Divigel on the Liver?


    Divigel has very mild side effects on the liver.

    Mild
  • What is the effect of Divigel on the Heart?


    Divigel can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Divigel with Other Drugs

Divigel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Divigel Contraindications

If you are suffering from any of the following diseases, you should not take Divigel unless your doctor advises you to do so -



Frequently asked Questions about Divigel

  • Is this Divigel habit forming or addictive?


    No, you will not get addicted to Divigel.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Divigel does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Yes, but take Divigel only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Divigel cannot treat any kind of mental disorder.

    No

Divigel Interactions with Food and Alcohol

  • Interaction between Food and Divigel


    Information is not available on the interaction of any foods with Divigel, due to a lack of research on this.

    Unknown
  • Interaction between Alcohol and Divigel


    Information about the interaction of Divigel and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Divigel

Question about 5 years ago

Can I discontinue Divigel on my own without doctors advice?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

No, Divigel should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

Question almost 5 years ago

Can Divigel cause cancer?

Dr. MBBS , General Physician, Other, Infectious Disease

Long-term use of Divigel at higher doses increases the risk of endometrial cancer in postmenopausal women. It depends on the duration of treatment and doses of this drug. If you are taking this drug for prolonged duration and having recurring abnormal vaginal bleeding then consult it with your doctor without further delay.

Question over 4 years ago

Does Divigel cause spotting?

Dr. Faisal Mukhtar MBBS, PG Dip, DNB , Ophthalmology

Yes, Divigel may cause spotting or intermenstrual bleeding, it has been associated with spotting but it occurs in a few cases only. It is a rare side effect of this drug. This might occur due to hormonal imbalance. 

Question about 4 years ago

Can I take Divigel and levothyroxine at the same time?

Dr. MBBS , General Physician, Other, Infectious Disease

Yes Divigel can be taken along with levothyroxine at the same time. Levothyroxine does not appear to interfere with the efficacy of Divigel. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question about 5 years ago

What is Divigel?

Dr. Ram Saini MD, MBBS , General Physician

Divigel is a brand name of estradiol and it comes in the form of a tablet (solid unit dosage form). It belongs to the class of drug known as estrogen. Divigel is a prescription drug which is used for hormone replacement therapy in menopausal women. It is also used for the prevention of postmenopausal osteoporosis.



See all substitutes for Divigel


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Estrace (estradiol)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 306-309

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 526-528



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