Durea

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  • Contains / Salt: Hydroxyurea (500 mg)
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Durea Information

Durea is a prescription medicine that is available as a Capsule. It is typically used for the treatment of Chronic Myelogenous Leukemia. Other than this, Durea has some other therapeutic uses, which have been discussed ahead.

The right dosage of Durea depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

Common side effects of Durea include Chills, Fever, Cough. Some other side effects of Durea have been listed ahead. Such side effects of Durea normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Durea is Severe for pregnant women and Severe for women who are breastfeeding. It is important to know if Durea has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Durea related warnings section.

Durea can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Durea in conditions like Anemia, Neutropenia, Blood Cancer.

Drug reaction of Durea with other medicines has been reported. Refer to the list below for further details.

In addition to the above precautions for Durea, it is important to know that it is not safe while driving, and is not habit-forming.



Durea Benefits & Uses

Durea is used to treat the following -

Other Benefits

Durea Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Chronic Myelogenous Leukemia (CML)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 30 mg/kg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Sickle Cell Disease
  • Before or After Meal: After Meal
  • Single Maximum Dose: 15 mg/kg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose may increased up to 5 mg/kg after 12 weeks of treatment


Durea Side Effects

Based on research, the following side effects have been observed when Durea is used -

Severe

Moderate

Common

Durea Related Warnings

  • Is the use of Durea safe for pregnant women?


    Durea shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Durea safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Durea. It should only be taken after medical advice.

    Severe
  • What is the effect of Durea on the Kidneys?


    Durea may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Durea on the Liver?


    Durea can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Durea on the Heart?


    Very few cases of side effects of Durea on the heart have been reported.

    Mild


Severe Interaction of Durea with Other Drugs

Durea should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Durea Contraindications

If you are suffering from any of the following diseases, you should not take Durea unless your doctor advises you to do so -



Frequently asked Questions about Durea

  • Is this Durea habit forming or addictive?


    No, there is no any evidence that Durea is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Durea you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Durea is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Durea is unable to treat or cure mental disorders.

    No

Durea Interactions with Food and Alcohol

  • Interaction between Food and Durea


    Taking Durea with food is safe.

    Safe
  • Interaction between Alcohol and Durea


    It is difficult to say anything about the effect of Durea and alcohol. No research has been done on this yet.

    Unknown


See all substitutes for Durea


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hydrea (hydroxyurea)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Droxia® (hydroxyurea)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Siklos (hydroxyurea)



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