Phenicol

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Phenicol Information

Phenicol, a prescription drug, is manufactured in various forms such as Suspension. It is typically used for the treatment of Bacterial Infections. Secondary and off-label uses of Phenicol have also been mentioned below.

The optimal dosage of Phenicol is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

While these are the most often observed Phenicol side effects, there are can be others also. These have been listed below. Usually, these side effects of Phenicol go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Phenicol's effect is Severe during pregnancy and Severe for lactating mothers. It is important to know if Phenicol has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Phenicol related warnings section.

Phenicol can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Phenicol in conditions like Kidney Disease, Liver Disease. The section on Phenicol contraindications lists all such conditions.

Drug reaction of Phenicol with other medicines has been reported. See below for a complete list.

You should also be aware that Phenicol is safe while driving, and is addiction.



Phenicol Benefits & Uses

Phenicol is used to treat the following -

Main Benefits

Other Benefits

Phenicol Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Typhoid Fever
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: 10 days
  • Special Instructions: strength 125 mg/5ml
Geriatric
  • Disease: Typhoid Fever
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: 10 days
  • Special Instructions: strength 125 mg/5ml
13 - 18 years (Adolescent)
  • Disease: Typhoid Fever
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: 10 days
  • Special Instructions: strength 125 mg/5ml
2 - 12 years (Child)
  • Disease: Typhoid Fever
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: 10 days
  • Special Instructions: strength 125 mg/5ml
Infant (1 month to 2 years)
  • Disease: Typhoid Fever
  • Before or After Meal: Either
  • Single Maximum Dose: 10 ml
  • Dosage Route: Oral
  • Frequency: 6 hourly
  • Course Duration: 10 days
  • Special Instructions: strength 125 mg/5ml

Phenicol Related Warnings

  • Is the use of Phenicol safe for pregnant women?


    Pregnant women may get severe side effects after taking Phenicol. If you are pregnant, do not take Phenicol without a doctor's advice.

    Severe
  • Is the use of Phenicol safe during breastfeeding?


    Taking Phenicol may lead to serious side effects if you are breastfeeding. Phenicol should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Phenicol on the Kidneys?


    Phenicol rarely affects the kidneys.

    Mild
  • What is the effect of Phenicol on the Liver?


    The liver can be affected by Phenicol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Phenicol only after medical advice.

    Moderate
  • What is the effect of Phenicol on the Heart?


    Phenicol can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Phenicol with Other Drugs

Phenicol should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Phenicol Contraindications

If you are suffering from any of the following diseases, you should not take Phenicol unless your doctor advises you to do so -



Frequently asked Questions about Phenicol

  • Is this Phenicol habit forming or addictive?


    No, there is no any evidence that Phenicol is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Phenicol since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, but consume Phenicol only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Phenicol is unable to treat or cure mental disorders.

    No

Phenicol Interactions with Food and Alcohol

  • Interaction between Food and Phenicol


    Some foods when eaten with Phenicol can alter the onset of actions. Discuss this with your doctor.

    Mild
  • Interaction between Alcohol and Phenicol


    Information about the interaction of Phenicol and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Phenicol

Question about 5 years ago

How does Phenicol work?

Dr. Sameer Awadhiya MBBS , Pediatrics

Phenicol contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Phenicol is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.

Question about 5 years ago

Can I discontinue Phenicol on my own without doctors advice?

Dr. Abhijit MBBS , General Physician

Discontinuing Phenicol on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.

Question almost 5 years ago

Can Phenicol cause nausea and vomiting?

Dr. Surender Kumar MBBS , General Physician

Rarely, Phenicol causes nausea and vomiting. It is a known side effect of this drug. For relief from nausea and vomiting try to take lime water, avoid eating spicy food even if it persists or becomes severe then discuss with your doctor.

Question almost 4 years ago

Is Phenicol an antibiotic?

Dr. MBBS , General Physician, Other, Infectious Disease

Yes, Phenicol is an antibiotic. It contains chloramphenicol which is a broad spectrum antibiotic that belongs to the class of drugs known as amphenicols. It is used for the prevention and treatment of various bacterial infections. It is mainly used in the treatment of parrot fever, rickettsial infection, cystic fibrosis, pneumonia, and also sometimes in the management of typhoid fever.

Question over 3 years ago

Can I take Phenicol with ranitidine?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Phenicol can be taken with ranitidine. No harmful drug interaction has been reported between them. It is safe to take Phenicol along with ranitidine if taken as directed by a doctor. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.



See all substitutes for Phenicol


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742

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