Xifapill 400 Tablet

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Xifapill 400 Tablet Information

Xifapill 400 Tablet, a prescription drug, is manufactured in various forms such as Tablet. Hepatic Encephalopathy are some of its major therapeutic uses. The alternative uses of Xifapill 400 Tablet have also been explained below.

Medical history of the patient along with age and gender determines the dosage of Xifapill 400 Tablet. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

The most common side effects of Xifapill 400 Tablet are Flatulence, Bloating or fullness, Constipation. Apart from the aforementioned side effects, Xifapill 400 Tablet can also lead to other problems, which have been listed below. Usually, these side effects of Xifapill 400 Tablet go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Xifapill 400 Tablet has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Xifapill 400 Tablet related warnings talks about Xifapill 400 Tablet's effects on the liver, heart and kidney.

Other conditions have been mentioned below in the Xifapill 400 Tablet contraindications section.

Additionally, Xifapill 400 Tablet may also adversely react with other medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Xifapill 400 Tablet is considered safe while driving, and is addictive.



Xifapill 400 Tablet Benefits & Uses

Xifapill 400 Tablet is used to treat the following -

Main Benefits

Other Benefits

Xifapill 400 Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Xifapill 400 Tablet Related Warnings

  • Is the use of Xifapill 400 Tablet safe for pregnant women?


    Xifapill can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Xifapill 400 Tablet safe during breastfeeding?


    Xifapill may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Xifapill 400 Tablet on the Kidneys?


    Using Xifapill does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Xifapill 400 Tablet on the Liver?


    Xifapill has very mild side effects on the liver.

    Mild
  • What is the effect of Xifapill 400 Tablet on the Heart?


    Xifapill is completely safe for the heart.

    Safe


Xifapill 400 Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Xifapill 400 Tablet unless your doctor advises you to do so -



Frequently asked Questions about Xifapill 400 Tablet

  • Is this Xifapill 400 Tablet habit forming or addictive?


    No, there is no any evidence that Xifapill 400 Tablet is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Xifapill 400 Tablet does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Xifapill 400 Tablet should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Xifapill 400 Tablet is unable to treat or cure mental disorders.

    No

Xifapill 400 Tablet Interactions with Food and Alcohol

  • Interaction between Food and Xifapill 400 Tablet


    You can take Xifapill 400 Tablet with food.

    Safe
  • Interaction between Alcohol and Xifapill 400 Tablet


    It is difficult to say anything about the effect of Xifapill 400 Tablet and alcohol. No research has been done on this yet.

    Unknown


Frequently asked Questions about Xifapill 400 Tablet

Question about 5 years ago

Can Xifapill cause headache?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes, Xifapill might cause a headache. It is a rare side effect of this drug. However, the exact cause of a headache is still unknown. If you experience a severe headache after taking this drug, take a mild painkiller, apply balm and take rest even after this if the pain does not subside then discuss with your doctor without any further delay.

Question about 5 years ago

Can I take Xifapill without consulting a doctor?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

No, Xifapill is a prescription drug and an antibiotic, hence do not take this drug without consulting doctor to avoid bacterial resistance and unpleasant side effects. It can be harmful for patients to take this medicine without the doctor's advice.

Question over 4 years ago

Does Xifapill work for SIBO (Small Intestinal Bacterial Overgrowth)?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

The use of Xifapill for the treatment of small intestinal bacterial overgrowth (SIBO) is not approved and scientific evidence supporting its use for SIBO is not sufficient.

Question almost 5 years ago

Does Xifapill cause weight gain?

Dr. Haleema Yezdani MBBS , General Physician

No, Xifapill does not cause weight gain. It has not been reported by the patients who are taking this drug but Xifapill has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.

Question over 5 years ago

How does Xifapill work?

Dr. Anand Singh MBBS , General Physician

Xifapill works by inhibiting the bacterial protein synthesis which is essential for bacterial growth. The absence of these proteins results in stunned bacterial growth due to which bacteria is not able to survive. For hepatic encephalopathy Xifapill works by inhibiting the growth of enteric ammonia-producing bacteria which are present in our gut, this results in the indirect reduction of serum ammonia level. In irritable bowel syndrome with diarrhea, how Xifapill works are still unknown but it is presumed that it works by changing the bacterial flora in small intestine and reduction in gas.



See all substitutes for Xifapill



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

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