Megaplat 50 Injection Information

Megaplat 50 Injection is a prescription drug, available for use as Injection. It is typically used for the treatment of Colorectal Cancer. Secondary and off-label uses of Megaplat 50 Injection have also been mentioned below.

The right dosage of Megaplat 50 Injection depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

Some other side effects of Megaplat 50 Injection have been listed ahead. These side effects of Megaplat 50 Injection are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Megaplat 50 Injection's effect is Severe during pregnancy and Severe for lactating mothers. Warnings related to Megaplat 50 Injection's effects on the liver, heart and kidney, if any, have been listed below.

Megaplat 50 Injection is not recommended if you suffer from certain medical conditions as it can have adverse effects. Arrhythmia are examples of such conditions. Other contraindications of Megaplat 50 Injection have been discussed in the sections ahead.

Additionally, Megaplat 50 Injection may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Megaplat 50 Injection is not safe while driving, and is is not addictive in nature.

Megaplat Benefits & Uses
Megaplat Dosage & How to Take
Megaplat Side Effects
Megaplat Related Warnings
Megaplat Contraindications
Frequently asked Questions about Megaplat
Megaplat Interactions with Food and Alcohol

Megaplat 50 Injection Benefits & Uses

Megaplat 50 Injection is used to treat the following -

Other Benefits

Colorectal Cancer

Megaplat 50 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Megaplat 50 Injection Related Warnings

Is the use of Megaplat 50 Injection safe for pregnant women?

Pregnant women may get severe side effects after taking Megaplat. If you are pregnant, do not take Megaplat without a doctor's advice.

Severe
Is the use of Megaplat 50 Injection safe during breastfeeding?

Megaplat may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Megaplat 50 Injection on the Kidneys?

Very few cases of side effects of Megaplat on kidney have been reported.

Mild
What is the effect of Megaplat 50 Injection on the Liver?

Megaplat can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Megaplat 50 Injection on the Heart?

Megaplat can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate

Megaplat 50 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Megaplat 50 Injection unless your doctor advises you to do so -

Heart Disease
Liver Disease
Neutropenia
Peripheral Neuropathy
Arrhythmia

Frequently asked Questions about Megaplat 50 Injection

Is this Megaplat 50 Injection habit forming or addictive?

Forming a habit of Megaplat 50 Injection has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Megaplat 50 Injection as you may feel sleepy.

Dangerous
Is it safe?

Yes, but consume Megaplat 50 Injection only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Megaplat 50 Injection is unable to treat or cure mental disorders.

No

Megaplat 50 Injection Interactions with Food and Alcohol

Interaction between Food and Megaplat 50 Injection

Taking Megaplat 50 Injection with food is safe.

Safe
Interaction between Alcohol and Megaplat 50 Injection

Consult your doctor before consuming alcohol while taking Megaplat 50 Injection as it can have severe side effects.

Severe

See all substitutes for Megaplat

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)

Megaplat 50 Injection