Hydralazine Hydrochloride

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Hydralazine Hydrochloride Information

Hydralazine Hydrochloride, a prescription drug, is manufactured in various forms such as Injection. Primarily, it is used for the treatment of High BP. Hydralazine Hydrochloride also has some secondary and off-label uses. These are listed below.

The right dosage of Hydralazine Hydrochloride depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Hydralazine Hydrochloride are Jaw Pain, Chest Discomfort, Shortness of Breath. Apart from the aforementioned side effects, Hydralazine Hydrochloride can also lead to other problems, which have been listed below. These side effects of Hydralazine Hydrochloride are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Hydralazine Hydrochloride's effect is Moderate during pregnancy and Safe for lactating mothers. In addition, Hydralazine Hydrochloride's effects on the liver, heart and kidney are discussed below in the Hydralazine Hydrochloride related warnings section.

Hydralazine Hydrochloride is contraindicated in people with pre-existing medical conditions like Angina, Heart Failure as it can result in adverse effects. Some other conditions that can be affected by Hydralazine Hydrochloride are listed in the contraindications section below.

Drug reaction of Hydralazine Hydrochloride with other medicines has been reported. See below for a complete list.

In addition to the above precautions for Hydralazine Hydrochloride, it is important to know that it is not safe while driving, and is not habit-forming.



Hydralazine Hydrochloride Benefits & Uses

Hydralazine Hydrochloride is used to treat the following -

Main Benefits

Other Benefits

Hydralazine Hydrochloride Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: High Blood Pressure
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 20 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: used in hypertensive emergency
Geriatric
  • Disease: High Blood Pressure
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 20 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: used in hypertensive emergency
Adult(Female)
  • Disease: Preeclampsia and Eclampsia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 10 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: used in hypertensive emergency

Hydralazine Hydrochloride Related Warnings

  • Is the use of Hydralazine Hydrochloride safe for pregnant women?


    Pregnant women may experience moderate side effects from Hydralazine Hydrochloride. It is best to stop taking Hydralazine Hydrochloride immediately and inform your doctor if you notice any discomfort.

    Moderate
  • Is the use of Hydralazine Hydrochloride safe during breastfeeding?


    Hydralazine Hydrochloride is completely safe for breastfeeding women.

    Safe
  • What is the effect of Hydralazine Hydrochloride on the Kidneys?


    Hydralazine Hydrochloride has very mild side effects on the kidneys.

    Mild
  • What is the effect of Hydralazine Hydrochloride on the Liver?


    Hydralazine Hydrochloride has very mild side effects on the liver.

    Mild
  • What is the effect of Hydralazine Hydrochloride on the Heart?


    Hydralazine Hydrochloride may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Hydralazine Hydrochloride with Other Drugs

Hydralazine Hydrochloride should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Chlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine

    Moderate



    Hydralazine Hydrochloride Contraindications

    If you are suffering from any of the following diseases, you should not take Hydralazine Hydrochloride unless your doctor advises you to do so -



    Frequently asked Questions about Hydralazine Hydrochloride

    • Is this Hydralazine Hydrochloride habit forming or addictive?


      No, there is no any evidence that Hydralazine Hydrochloride is addictive.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      You may feel sleepy or tired after taking Hydralazine Hydrochloride. So it is best to avoid driving.

      Dangerous
    • Is it safe?


      Yes, but take Hydralazine Hydrochloride only as per medical advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      No, the use of Hydralazine Hydrochloride in mental disorders is not effective.

      No

    Hydralazine Hydrochloride Interactions with Food and Alcohol

    • Interaction between Food and Hydralazine Hydrochloride


      Taking Hydralazine Hydrochloride with food does not harm your health.

      Safe
    • Interaction between Alcohol and Hydralazine Hydrochloride


      No research has been done on this till date. Therefore, it is not known what the effect of taking Hydralazine Hydrochloride with alcohol will be.

      Unknown


    Frequently asked Questions about Hydralazine Hydrochloride

    Question over 4 years ago

    Does Hydralazine Hydrochloride cause erectile dysfunction (ED) or impotence?

    Dr. Manoj Meena MBBS , General Physician

    Very rarely, Hydralazine Hydrochloride causes erectile dysfunction (ED) or impotence. However, the exact cause of erectile dysfunction or impotence is unknown. This effect is temporary, reversible and unharmful in nature and it goes away after discontinuation of this drug.

    Question about 5 years ago

    Can I take Hydralazine Hydrochloride without consulting a doctor?

    Dr. Ajay Kumar MBBS, MD , General Physician

    No, Hydralazine Hydrochloride is a prescription drug, so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it can cause very unpleasant side effects. Hence, the patient should seek doctors advice before taking this medication by himself or herself.

    Question over 4 years ago

    Is Hydralazine Hydrochloride used to treat anxiety?

    Dr. Kumawat Vijay Kumar MBBS , General Physician

    No, Hydralazine Hydrochloride is not used to treat anxiety. It is used in the management of hypertension (high blood pressure) and congestive heart failure.

    Question almost 5 years ago

    Does Hydralazine Hydrochloride cause headache?

    Dr. Bharat MBBS , General Physician

    Yes, Hydralazine Hydrochloride may cause a headache. It is a common side effect of this drug. However, the exact cause behind a headache is unknown. If you experience a severe headache after taking this drug, take a mild painkiller, apply balm and complete rest even after this if the pain does not subside then discuss with your doctor immediately.

    Question almost 5 years ago

    Does Hydralazine Hydrochloride slow heart rate (bradycardia)?

    Dr. Gaurav MBBS , General Physician

    No, Hydralazine Hydrochloride does not slow or decrease heart rate (bradycardia). It has not been reported by the patients who are taking this drug. In fact, it can cause increased heart rate (tachycardia) that occurs as a reflex response to decreased peripheral resistance (resistance of the arteries to blood flow).



    See all substitutes for Hydralazine Hydrochloride


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hydralazine hydrochloride

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 566-567

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 651-653

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