Santron

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Santron Information

Santron is a prescription medicine that is available as a Injection. Primarily, it is used for the treatment of Nausea and Vomiting.

The correct dosage of Santron depends on the patient's age, gender, and medical history. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

While these are the most often observed Santron side effects, there are can be others also. These have been listed below. Such side effects of Santron normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Santron's effect during pregnancy is Safe and Mild while nursing. Warnings related to Santron's effects on the liver, heart and kidney, if any, have been listed below.

Individuals suffering from medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency must refrain from the use of Santron since this can cause severe adverse effects. Other conditions have been mentioned below in the Santron contraindications section.

Drug interactions for Santron have been reported in the medical literature. Refer to the list below for further details.

In addition to the above precautions for Santron, it is important to know that it is not safe while driving, and is not habit-forming.



Santron Benefits & Uses

Santron is used to treat the following -

Santron Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Santron Related Warnings

  • Is the use of Santron safe for pregnant women?


    Pregnant women can take Santron safely.

    Safe
  • Is the use of Santron safe during breastfeeding?


    Santron may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Santron on the Kidneys?


    Santron does not damage the kidneys.

    Safe
  • What is the effect of Santron on the Liver?


    The liver can be affected by Santron. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Santron only after medical advice.

    Moderate
  • What is the effect of Santron on the Heart?


    You may experience side effects on your heart after taking Santron. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of Santron with Other Drugs

Santron should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Santron Contraindications

If you are suffering from any of the following diseases, you should not take Santron unless your doctor advises you to do so -



Frequently asked Questions about Santron

  • Is this Santron habit forming or addictive?


    No, there is no any evidence that Santron is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Santron you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Santron is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Santron for mental disorders.

    No

Santron Interactions with Food and Alcohol

  • Interaction between Food and Santron


    Taking Santron with food is safe.

    Safe
  • Interaction between Alcohol and Santron


    Consuming Santron with alcohol can have many serious effects on your body.

    Severe


Frequently asked Questions about Santron

Question about 5 years ago

Is Santron safe for children?

Dr. R.K Singh MBBS , Diabetology

Yes, Santron is safe to be used in children from 6 months to 12 years of age. Apart from preventing nausea and vomiting related to chemotherapy and radiation, Santron can be used in this population group for managing acute gastritis. Acute gastritis presents itself as a self-limited infection with vomiting leading to dehydration and electrolyte imbalances. Always check with a child specialist and do not administer this drug yourself.

Question about 5 years ago

Can Santron be taken for irritable bowel syndrome with diarrhea?

Dr. Vipin Khadse MBBS , General Physician

Yes, Santron can be taken for the treatment of irritable bowel syndrome with diarrhea. Irritable bowel syndrome is a common gastrointestinal disorder affecting a lot of people. It causes gas, abdominal discomfort and changes in the bowel movement like diarrhea or constipation. The disease can be controlled by altering the diet and eating more of fibre and less of fats, alcohol, caffeine and spicy food. Increasing physical activity and reducing stress can also help greatly. 

Question about 5 years ago

How does Santron work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Santron belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

Question almost 5 years ago

Does Santron cause drowsiness?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Santron may cause drowsiness because this drug has been reported to induce sleep. Ensure you do not drive or do some high precision work. To avoid excessive drowsiness with this medicine you are encouraged to take adequate night-time sleep, keeping distractions out of the bedroom, going to sleep and getting up at consistent times, eating light at lunchtime, putting in some form of a physical activity, avoiding taking naps during the day, and avoiding alcohol at night.

Question over 4 years ago

Does Santron cause headache?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, headache is one of the common side effects of Santron. Apply balms and take a mild painkiller if a headache is of throbbing nature. Additionally, headaches can be prevented by doing yoga and meditation, by keeping away from electronic gadgets and computers, by eating light food and listening to relaxing music.



See all substitutes for Santron


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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