Nkacin

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  • Contains / Salt: Amikacin (500 mg)
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Nkacin Information

Nkacin is a commercial drug that is prescribed in the form of Injection. Urinary Tract Infection are some of its major therapeutic uses. Secondary and off-label uses of Nkacin have also been mentioned below.

The right dosage of Nkacin depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

Some other side effects of Nkacin have been listed ahead. Usually, these side effects of Nkacin go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

Nkacin's effect during pregnancy is Severe and Unknown while nursing. In addition, Nkacin's effects on the liver, heart and kidney are discussed below in the Nkacin related warnings section.

Individuals suffering from medical conditions like Dehydration, Parkinson's Disease, Hearing Loss must refrain from the use of Nkacin since this can cause severe adverse effects. Other conditions have been mentioned below in the Nkacin contraindications section.

Drug interactions for Nkacin have been reported in the medical literature. Refer to the list below for further details.

In addition to the above precautions for Nkacin, it is important to know that it is safe while driving, and is habit-forming.



Nkacin Benefits & Uses

Nkacin is used to treat the following -

Main Benefits

Other Benefits

Nkacin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Nkacin Related Warnings

  • Is the use of Nkacin safe for pregnant women?


    Nkacin should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Nkacin safe during breastfeeding?


    In the absence of any scientific study about the side effects of Nkacin in breastfeeding women, information on safety of Nkacin is unavailable.

    Unknown
  • What is the effect of Nkacin on the Kidneys?


    Consumption of Nkacin can harm the kidneys. So it is important to take medical advice beforehand.

    Severe
  • What is the effect of Nkacin on the Liver?


    Side effects of Nkacin rarely affect the liver.

    Mild
  • What is the effect of Nkacin on the Heart?


    Very few cases of side effects of Nkacin on the heart have been reported.

    Mild


Severe Interaction of Nkacin with Other Drugs

Nkacin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Nkacin Contraindications

If you are suffering from any of the following diseases, you should not take Nkacin unless your doctor advises you to do so -



Frequently asked Questions about Nkacin

  • Is this Nkacin habit forming or addictive?


    No, you will not get addicted to Nkacin.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Nkacin since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, Nkacin is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Nkacin in mental disorders is not effective.

    No

Nkacin Interactions with Food and Alcohol

  • Interaction between Food and Nkacin


    Taking Nkacin with food does not harm your health.

    Safe
  • Interaction between Alcohol and Nkacin


    No research has been done on this till date. Therefore, it is not known what the effect of taking Nkacin with alcohol will be.

    Unknown


Frequently asked Questions about Nkacin

Question over 4 years ago

Does Nkacin cover pseudomonas?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Nkacin is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Nkacin will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.

Question almost 5 years ago

Does Nkacin cause constipation?

Aakash Shah MBBS, MBBS , General Physician

No, Nkacin does not cause constipation in patients who are taking it. However, if you are experiencing constipation after taking this drug then inform your doctor and take precautionary methods such as eating fibrous foods to avoid constipation.

Question over 4 years ago

Is Nkacin ototoxic?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Nkacin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.

Question almost 5 years ago

Does Nkacin cause thrombocytopenia?

Dr. Gaurav MBBS , General Physician

Occasionally, Nkacin can cause drug-induced thrombocytopenia (blood clot formation in the vessel). However, if you experience severe thrombocytopenia after taking this medicine, please immediately seek medical help.

Question about 5 years ago

How does Nkacin work?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Nkacin is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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