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What is bladder cancer?

Bladder cancer is a common type of cancer seen in adults in the age group of 50 to 70 years. It ranks sixth amongst the most commonly occurring cancers in India. Bladder cancer is an abnormal growth of cells in the bladder lining. Approximately 15% of cancer cases occurring due to tobacco use are of bladder cancer. Removal of tumour from the bladder (transurethral resection of bladder tumour or TURBT) results in improvement in a majority of the bladder cancer cases. However, cancer recurs in more than 50% of cases, and in 20% of these, cancer spreads into the tissue surrounding the bladder (muscle-invasive bladder cancer). TURBT, chemotherapy and radiation therapy are the most commonly used treatment options depending on the grade of cancer.

What are its main signs and symptoms?

Bladder cancer is suspected in the presence of the following signs and symptoms:

  • Haematuria or blood in urine, usually not associated with pain. Urine appears rusty or bright red in colour
  • Increase in the frequency of urination Read more: Frequent urination treatment
  • Sudden urge to pass urine
  • Pain or burning sensation while passing urine
  • Back pain, bone pain, oedema or swelling of the legs occurs when cancer spreads beyond the urinary bladder
  • Weight loss in the advanced stage of cancer

Other causes of haematuria (blood in the urine) include:

What are the main causes?

Causes attributed to the development of bladder cancer include:

  • Tobacco consumption
  • Exposure to chemicals like aniline dyes and benzidine, which is used in the manufacture of paints, textiles, rubber, plastics, etc.
  • Radiotherapy used in the treatment of intestinal cancer
  • Medicines used in chemotherapy
  • A few other causes include infection of bladder (schistosomiasis), diabetes, chronic catheterisation and menopause before 45 years of age

How is it diagnosed and treated?

In addition to a detailed history and physical examination, diagnosis of bladder cancer is made on the basis of the following investigations:

  • Cystoscopy is done to view the tumour inside the bladder.
  • the tumorous tissue taken out during cystoscopy is examined under a microscope to identify the stage and grade of cancer.
  • Computed tomography scan and magnetic resonance imaging give a detailed image of the tumour.
  • Intravenous urogram takes an X-ray image of the bladder while the dye flows through the urinary tract to detect the tumour.
  • Urine sample is examined under microscope to detect cancer cells in the urine.
  • Tumour marker test (bladder tumour antigen) is done to detect proteins or antigens secreted by cancer cells.

Bladder cancer, that is limited to the innermost lining of the urinary bladder is called non–muscle-invasive bladder cancer, whereas cancer that spreads to the deeper layers of the bladder (through the muscle layer, fat and connective tissue) and to the other organs around the urinary bladder is called muscle-invasive bladder cancer. Grading helps in analysing the spread of cancer. High-grade cancer is more prone to spread compared to low-grade cancer.

Treatment depends on the stage and grade of bladder cancer. It generally includes:

  • TURBT
  • Surgery is done to remove the tumour when the cancer is limited to the superficial layer of the urinary bladder. Low-grade non–muscle-invasive cancers respond positively to this surgery.
  • Chemotherapy: The chemotherapy drug is injected directly into the bladder after TURBT to prevent recurrence. Doctors advise chemotherapy in low to medium risk cancer depending on the stage of cancer.
  • Radiation therapy: High-grade bladder cancers that have spread generally require radiation therapy in addition to chemotherapy.
  • Immunotherapy: Some cases of early-stage cancer are also treated with a modified form of BCG vaccine after TURBT.
  • A part or whole of the urinary bladder is removed surgically if cancer fails to respond to treatment with BCG.
  1. Medicines for Bladder Cancer
  2. Doctors for Bladder Cancer
Dr. Arabinda Roy

Dr. Arabinda Roy

ऑन्कोलॉजी

Dr. Ashutosh Gawande

Dr. Ashutosh Gawande

ऑन्कोलॉजी

Dr. C. Arun Hensley

Dr. C. Arun Hensley

ऑन्कोलॉजी

Medicines for Bladder Cancer

Medicines listed below are available for Bladder Cancer. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
CelplatCelplat 10 Mg Injection94.0
CisplatCisplat 10 Mg Injection94.0
CisteenCisteen 10 Mg Injection81.0
CizcanCizcan 10 Mg Injection77.0
CytoplatinCytoplatin 10 Mg Injection93.0
KemoplatKemoplat 10 Mg Injection84.0
PlatikemPlatikem 10 Mg Injection187.0
Platikem NovoPlatikem Novo 100 Mg Injection886.0
Platin (Cadila)Platin 10 Mg Injection78.0
PlatinexPlatinex 10 Mg Injection64.0
CisglanCisglan 50 Mg Infusion452.0
Oncoplatin AqOncoplatin Aq 10 Mg Injection87.0
PlatifirstPlatifirst 10 Mg Injection107.0
PlatiparPlatipar 10 Mg Injection150.0
SlatinSlatin 50 Mg Infusion315.0
UniplatinUniplatin 10 Mg Injection106.0
AlimtaAlimta 100 Mg Injection17683.0
PemcurePemcure 100 Mg Injection1500.0
PemexPemex 500 Mg Injection25400.0
PemgemPemgem 100 Mg Injection4882.47
PemmetPemmet 100 Mg Injection1389.26
PemnatPemnat 100 Mg Injection4900.0
PemotidePemotide 100 Mg Injection2362.5
PexetrustPexetrust 100 Mg Injection1812.5
PexitazPexitaz 100 Mg Injection2422.17
PleumetPleumet 100 Mg Injection4663.47
PamiglanPamiglan 500 Mg Infusion156451.0
PemecadPemecad 100 Mg Injection6040.2
PemeetronPemeetron 100 Mg Injection5142.86
PemexarPemexar 100 Mg Injection5000.0
PemproPempro 100 Mg Injection8500.0
PexotraPexotra 100 Mg Injection2350.0
TemeranTemeran 100 Mg Injection1980.0
ZupemedZupemed 100 Mg Injection4333.33
AdriamycinAdriamycin 10 Mg Injection221.61
AdriblastinaAdriblastina Injection1309.52
Adronex RdAdronex Rd 10 Mg Injection185.71
AdrosalAdrosal 10 Mg Injection196.43
CadriaCadria 10 Mg Injection166.66
CardiaroneCardiarone 100 Mg Tablet65.47
DoxilydDoxilyd 10 Mg Injection119.04
DoxohopeDoxohope 20 Mg Injection8163.26
DoxorexDoxorex 10 Mg Injection321.75
Doxorubicin (Dr. Reddys)Doxorubicin 10 Mg Injection116.66
DoxorubicinDoxorubicin 10 Mg Injection200.0
DoxorubinDoxorubin 10 Mg Injection130.95
DoxotarDoxotar 10 Mg Injection285.0
DoxoteroDoxotero 10 Mg Injection165.0
DoxulipDoxulip 20 Mg Injection7890.0
DoxutecDoxutec 10 Mg Injection170.0
DuxocinDuxocin 10 Mg Injection190.94
LyphidoxLyphidox 10 Mg Injection198.91
MetodoxMetodox 10 Mg Injection63.09
OncodriaOncodria 10 Mg Injection199.64
PiglitPiglit 2 Mg Injection6184.52
ZodoxZodox 10 Mg Injection196.19
ZubidoxZubidox 10 Mg Injection200.0
LyomitLyomit 10 Mg Injection430.83
Mitomycin CMitomycin C 10 Mg Injection522.0
OncocinOncocin 10 Mg Injection333.33
6 TG6 Tg 40 Mg Tablet300.0
AdrimAdrim 10 Mg Injection214.28
DoxiglanDoxiglan 50 Mg Injection999.0

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