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What is a neuroendocrine tumour?

Neuroendocrine tumours also called as carcinoids are tumours of cells which release hormones as well as have characteristics of nerves, called neuroendocrine cells. The growth of these tumours is often slow. They can develop in any organ of the body. These can be malignant (cancerous) or benign (non-cancerous).

What are its main signs and symptoms?

Depending upon the location of tumour, symptoms may vary. Below are some common symptoms which occur regardless of location

What are the main causes?

The exact cause of neuroendocrine tumours is not known. The possibility of developing neuroendocrine tumour increases if one of the below-inherited conditions are present:

  • Multiple endocrine neoplasia type 1
  • Neurofibromatosis type 1
  • Von Hippel-Lindau syndrome

How is it diagnosed and treated?

Diagnosis of neuroendocrine disease can be done by following tests:

  • Blood tests
  • Biopsy of tissue
  • Genetic testing and counselling
  • Scans which includes:
    • Ultrasound
    • Computerised tomography
    • Magnetic resonance imaging
    • Positron emission tomography
    • Octreotide scans – in this scan a mild radioactive liquid is injected in the veins and camera is utilized to detect the presence of cancerous cells
    • Laparoscopy
    • Nuclear medicine imaging

The treatment of neuroendocrine disease depends upon the location, intensity of a tumour and overall health status of patient. Below are the treatments available for this disease:

  • Surgery: Localized tumours can be removed by surgery and is considered as the first line of therapy.
  • Chemotherapy, hormone therapy and/or targeted therapy are used to treat a complicated or severe neuroendocrine tumour.
  • Medication: Somatostatin analogues (octreotide or lanreotide) stop the growth many hormones and reduce the intensity of symptoms and slow the disease progression.
  • Radiotherapy: reduce a tumour or stop it growing by blocking its blood supply using X- rays or gamma rays.

 

  1. Medicines for Neuroendocrine Tumour
  2. Doctors for Neuroendocrine Tumour
Dr. Susovan Banerjee

Dr. Susovan Banerjee

ऑन्कोलॉजी

Dr. Rajeev Agarwal

Dr. Rajeev Agarwal

ऑन्कोलॉजी

Dr. Nitin Sood

Dr. Nitin Sood

ऑन्कोलॉजी

Medicines for Neuroendocrine Tumour

Medicines listed below are available for Neuroendocrine Tumour. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
EvertorEvertor 10 Mg Tablet23732
AdvacanAdvacan 0.25 Mg Tablet0
AfinitorAfinitor 10 Mg Tablet0
BoletraazBoletraaz 10 Mg Tablet16000
CerticanCertican 0.25 Mg Tablet631
EvelimusEvelimus 10 Mg Tablet23520
EvergrafEvergraf 0.25 Mg Tablet502
EvermilEvermil 10 Mg Tablet24108
VolantisVolantis 10 Mg Tablet15252

Do you or anyone in your family have this disease? Please do a survey and help others

References

  1. National Health Service [Internet]. UK; Neuroendocrine tumours.
  2. Canadian Cancer Society [Internet]: Toronto,Canada; Neuroendocrine tumours.
  3. National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Neuroendocrine tumor.
  4. National Organization for Rare Disorders [Internet]; Neuroendocrine tumor.
  5. Oronsky B, Ma PC, Morgensztern D, Carter CA. Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas. Neoplasia. 19(12):991-1002. doi: 10.1016/j.neo.2017.09.002. Epub 2017 Nov 5. PubMed PMID: 29091800; PubMed Central PMCID: PMC5678742.
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