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What is skin discolouration?

Skin discolouration refers to irregular patches of changed skin colour. Skin discolouration is a relatively common problem and can be due to various causes like injury, inflammation or more serious underlying illness. Skin discolouration happens due to variable levels of melanin in the skin.

What are its main signs and symptoms?

Depending on the cause, these patches of skin discolouration can have varying degrees of symptoms, which include:

  • Dark coloured or light coloured or both types of patches on the skin
  • Itching
  • Redness
  • Reduced sensation or loss of sensation over the patches
  • Hyperaesthesia (increased sensitivity)

What are the main causes?

Skin discolouration is caused by a wide array of conditions, which range from simple allergies to severe autoimmune diseases. Some of the common causes include:

How is it diagnosed and treated?

A proper medical examination of the skin discolouration along with a medical history usually hints at the diagnosis, but certain investigations are required to confirm the diagnosis and provide appropriate treatment. These investigations include:

  • Blood investigations – Certain investigations to check for allergies and autoimmune diseases. These investigations include complete blood count (CBC), C-reactive protein (CRP), anti-nuclear antibodies (ANA).
  • Wood’s lamp examination – This test helps in identifying bacterial and fungal infections.
  • Skin biopsy – This helps in examining the cells under the microscope.

The treatment criteria purely depend on the cause of the disease. Once the cause is found, it is usually easy to clear the discolouration. Treatment aims at the underlying disease, which will automatically clear the discolouration. However, this may not be possible in many conditions. There are certain medications that help in removing this discolouration, which include:

  • Local applications – Topical application of vitamin A, vitamin E or hydroquinone helps in clearing the dark patches.
  • Chemical peeling – Certain chemicals like glycolic acid or salicylic acid can help in removing the outer layer of the skin (which is usually discoloured).
  • Laser therapy – Laser therapy also helps in lightening the dark patches.
  1. Medicines for Skin Discolouration

Medicines for Skin Discolouration

Medicines listed below are available for Skin Discolouration. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
ADEL 38 Apo-Spast DropADEL 38 Apo-Spast Drop200
Schwabe Crotalus horridus CHSchwabe Crotalus horridus 1000 CH96
Schwabe Ammi visnaga MTSchwabe Ammi visnaga MT 284
Bjain Ammi Visnaga DilutionBjain Ammi Visnaga Dilution 1000 CH175
Dr. Reckeweg Crotalus Hor DilutionDr. Reckeweg Crotalus Hor Dilution 1000 CH136
Adel Crotalus Horridus DilutionAdel Crotalus Horridus Dilution 1000 CH162
CutihydeCutihyde 3% W/V Cream0
Depig F (Intermed)Depig F (Intermed) Ointment32
DermofadeDermofade Cream0
EpiliteEpilite 5% Lotion114
Euskina PlusEuskina Plus Cream152
EuskinaEuskina Cream0
Melacare PlusMelacare Plus 2% W/W Cream248
Quinine DihydrochlorideQuinine Dihydrochloride 300 Mg Injection12
TanliteTanlite Cream36
Mela 3Mela 3 Cream126
Advan ThfAdvan Thf Cream156
Hyclean TfHyclean Tf Cream148
LitetoneLitetone Cream129
MelafectMelafect Cream280
XtraliteXtralite Ointment381
MelapikMelapik Cream117
O Fair PlusO Fair Plus Cream112

Do you or anyone in your family have this disease? Please do a survey and help others


  1. American Academy of Dermatology. Rosemont (IL), US; Variety of options available to treat pigmentation problems.
  2. National Institute of Arthritirs and Musculoskeletal and Skin Disease. [Internet]. U.S. Department of Health & Human Services; Autoimmune Diseases.
  3. National Institutes of Health; [Internet]. U.S. National Library of Medicine. Skin Pigmentation Disorders.
  4. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Abnormally dark or light skin.
  5. Thomas Habif et al. Skin Disease. 4th Edition September 2017; Elsevier

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