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Amikacin Injection is a prescription medicine. Primarily, it is used for the treatment of Urinary Tract Infection. Other than this, Amikacin Injection has some other therapeutic uses, which have been discussed ahead.
Medical history of the patient along with age and gender determines the dosage of Amikacin Injection. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.
Apart from the aforementioned side effects, Amikacin Injection can also lead to other problems, which have been listed below. Usually, these side effects of Amikacin Injection go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
It is also important to note that Amikacin Injection has a Severe effect for pregnant women and Unknown effect on lactating mothers. In addition, Amikacin Injection's effects on the liver, heart and kidney are discussed below in the Amikacin Injection related warnings section.
Amikacin Injection is contraindicated in people with pre-existing medical conditions like Dehydration, Parkinson's Disease, Hearing Loss as it can result in adverse effects. The section on Amikacin Injection contraindications lists all such conditions.
Besides this, Amikacin Injection may also have severe interaction with some medicines. Refer to the list below for further details.
In addition to these precautions, you may also note that Amikacin Injection is safe while driving, and is is addictive in nature.
Amikacin Injection is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Is the use of Amikacin Injection safe for pregnant women?
Pregnant women may get severe side effects after taking Amikacin. If you are pregnant, do not take Amikacin without a doctor's advice.
Is the use of Amikacin Injection safe during breastfeeding?
No research work has been carried out till date on effect of Amikacin on breastfeeding women. So it is not known whether taking Amikacin will cause side effects or not.
What is the effect of Amikacin Injection on the Kidneys?
Amikacin may have severe effects on your kidney, so do not take it without consulting your doctor.
What is the effect of Amikacin Injection on the Liver?
Amikacin has very mild side effects on the liver.
What is the effect of Amikacin Injection on the Heart?
Very few cases of side effects of Amikacin on the heart have been reported.
Amikacin Injection should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Amikacin Injection unless your doctor advises you to do so -
Is this Amikacin Injection habit forming or addictive?
No, there is no any evidence that Amikacin Injection is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Amikacin Injection since it does not cause drowsiness.
Is it safe?
Amikacin Injection should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Amikacin Injection is not used to treat mental disorders.
Interaction between Food and Amikacin Injection
Taking Amikacin Injection with food does not harm your health.
Interaction between Alcohol and Amikacin Injection
Due to lack of research, there is no information about the side effects of taking Amikacin Injection with alcohol.
No, Amikacin cannot be taken with penicillin. Because penicillin inactivates the Amikacin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amikacin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
Amikacin can be safely taken as prescribed by your doctor. Do not discontinue the medicine suddenly or take it longer than prescribed duration.
Yes, Amikacin can be taken with lidocaine. The clinical report suggests that no harmful drug-drug interactions have been observed between them so far. However, it doesn't mean that no interaction could exist between them. These two medicines are high alert drug so you must consult your doctor before taking Amikacin together.
Amikacin is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.
Yes, Amikacin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137