Amikoside

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Amikoside Information

Amikoside is a commercial drug that is prescribed in the form of Injection. Primarily, it is used for the treatment of Urinary Tract Infection. Amikoside also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Amikoside. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Apart from the aforementioned side effects, Amikoside can also lead to other problems, which have been listed below. Normally, these side effects of Amikoside are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.

Amikoside's effect during pregnancy is Severe and Unknown while nursing. It is important to know if Amikoside has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Amikoside related warnings section.

Amikoside is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Other conditions have been mentioned below in the Amikoside contraindications section.

Drug interactions for Amikoside have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Amikoside, it is important to know that it is safe while driving, and is habit-forming.



Amikoside Benefits & Uses

Amikoside is used to treat the following -

Main Benefits

Other Benefits

Amikoside Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amikoside Related Warnings

  • Is the use of Amikoside safe for pregnant women?


    Amikoside can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Amikoside safe during breastfeeding?


    Due to lack of research work on this topic, the side effects of Amikoside for breastfeeding women are not known.

    Unknown
  • What is the effect of Amikoside on the Kidneys?


    Amikoside may have severe effects on your kidney, so do not take it without consulting your doctor.

    Severe
  • What is the effect of Amikoside on the Liver?


    Amikoside may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Amikoside on the Heart?


    Amikoside is rarely harmful for the heart.

    Mild


Severe Interaction of Amikoside with Other Drugs

Amikoside should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Amikoside Contraindications

If you are suffering from any of the following diseases, you should not take Amikoside unless your doctor advises you to do so -



Frequently asked Questions about Amikoside

  • Is this Amikoside habit forming or addictive?


    Amikoside is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Amikoside will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, Amikoside is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Amikoside in mental disorders is not effective.

    No

Amikoside Interactions with Food and Alcohol

  • Interaction between Food and Amikoside


    You can take Amikoside with food.

    Safe
  • Interaction between Alcohol and Amikoside


    Information about the interaction of Amikoside and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Amikoside

Question almost 5 years ago

Does Amikoside cause diarrhea?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Amikoside has been reported to cause diarrhoea and it is a common side effect of this medicine. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after using this drug, discuss with your doctor immediately without any further delay. 

Question almost 5 years ago

Is Amikoside nephrotoxic?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Amikoside is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Amikoside taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Amikoside with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.

Question almost 5 years ago

Does Amikoside cause thrombocytopenia?

Dr. Gaurav MBBS , General Physician

Occasionally, Amikoside can cause drug-induced thrombocytopenia (blood clot formation in the vessel). However, if you experience severe thrombocytopenia after taking this medicine, please immediately seek medical help.

Question over 4 years ago

Is Amikoside ototoxic?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Amikoside has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.

Question about 5 years ago

How to take Amikoside?

Dr. Abhijit MBBS , General Physician

Do not self-administer Amikoside. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Amikoside please inform your doctor immediately. 



See all substitutes for Amikoside


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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