Knott Plus

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Knott Plus Information

Knott Plus is a prescription medicine that is available as a Tablet, Suspension. The alternative uses of Knott Plus have also been explained below.

Medical history of the patient along with age and gender determines the dosage of Knott Plus. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

The side effects typically associated with Knott Plus include Heartburn, Dizziness, Nausea or vomiting. Apart from the aforementioned side effects, Knott Plus can also lead to other problems, which have been listed below. Such side effects of Knott Plus normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Knott Plus is Moderate for pregnant women and Moderate for women who are breastfeeding. It is important to know if Knott Plus has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Knott Plus related warnings section.

Knott Plus is contraindicated in people with pre-existing medical conditions like Liver Disease as it can result in adverse effects.

Drug reaction of Knott Plus with other medicines has been reported. See below for a complete list.

In addition to the above precautions for Knott Plus, it is important to know that it is not safe while driving, and is not habit-forming.



Knott Plus Benefits & Uses

Knott Plus is used to treat the following -

Other Benefits

Knott Plus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 ml
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Nimesulide (100 mg) Paracetamol (325 mg)/ 5 ml, for course duration follow doctor's advice
2 - 12 years (Child)
  • Disease: Toothache
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 ml
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage strength: Nimesulide (50 mg) Paracetamol (125 mg)/ 5ml, for course duration follow doctor's advice

Knott Plus Related Warnings

  • Is the use of Knott Plus safe for pregnant women?


    Knott Plus may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Knott Plus again without your doctor's advice.

    Moderate
  • Is the use of Knott Plus safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Knott Plus. Immediately discontinue Knott Plus if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Knott Plus on the Kidneys?


    Consumption of Knott Plus can harm the kidneys. So it is important to take medical advice beforehand.

    Severe
  • What is the effect of Knott Plus on the Liver?


    Knott Plus can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Knott Plus on the Heart?


    There may be an adverse effect on the heart after taking Knott Plus. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

    Moderate


Severe Interaction of Knott Plus with Other Drugs

Knott Plus should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Knott Plus Contraindications

If you are suffering from any of the following diseases, you should not take Knott Plus unless your doctor advises you to do so -



Frequently asked Questions about Knott Plus

  • Is this Knott Plus habit forming or addictive?


    No, there is no any evidence that Knott Plus is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Knott Plus, you should not drive or work on any heavy machine, as Knott Plus can make you drowsy.

    Dangerous
  • Is it safe?


    Knott Plus is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Knott Plus is not used to treat mental disorders.

    No

Knott Plus Interactions with Food and Alcohol

  • Interaction between Food and Knott Plus


    Information is not available on the interaction of any foods with Knott Plus, due to a lack of research on this.

    Unknown
  • Interaction between Alcohol and Knott Plus


    No research has been done on this till date. Therefore, it is not known what the effect of taking Knott Plus with alcohol will be.

    Unknown


Frequently asked Questions about Knott Plus

Question about 5 years ago

Can I discontinue Knott Plus on my own or without doctors advice?

Aakash Shah MBBS, MBBS , General Physician

Discontinuation of Knott Plus on your own can cause unwanted side effects. You are recommended to always consult a doctor before discontinuing this medicine.

Question over 4 years ago

Can Knott Plus be taken with paracetamol?

Yes, Knott Plus can be taken with paracetamol. There is no drug interaction found between them.

Question over 5 years ago

What is Knott Plus?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Knott Plus is a brand name of nimesulide. It is a prescription drug that belongs to the class of medication called NSAIDs (Nonsteroidal Antiinflammatory Drugs). It has been used primarily for short-lasting painful inflammatory conditions like sports injuries, sinusitis, and other ear-nose-throat disorders, dental surgery, bursitis (Inflammation of the fluid-filled sac in the joints), lower backache, dysmenorrhoea (painful menstruation), post-operative pain, osteoarthritis and for fever.

Question about 5 years ago

Is Knott Plus an antibiotic?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Knott Plus is a painkiller, not an antibiotic drug. It is used to treat the short-lasting painful inflammatory conditions such as sports injuries, sinusitis, and other ear-nose-throat disorders, dental surgery, bursitis (Inflammation of the fluid-filled sac in the joints), lower backache, dysmenorrhoea (painful menstruation), post-operative pain, osteoarthritis, and fever.

Question almost 5 years ago

Does Knott Plus cause weight gain?

Dr. Yogesh Kumar MBBS , General Physician

No, Knott Plus does not cause weight gain because of medication increase in cellular metabolism occur in skeletal muscles (voluntary muscle), due to uncoupling of oxidative phosphorylation (loss of coupling between respiration and ATP (adenosine triphosphate which stores energy) production.



See all substitutes for Knott Plus


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 203-204

KD Tripathi. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 206-207

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Acetaminophen (acetaminophen)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ofirmev (acetaminophen)

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