Megaplat Information

Megaplat, a prescription drug, is manufactured in various forms such as Injection. It is typically used for the treatment of Colorectal Cancer. Secondary and off-label uses of Megaplat have also been mentioned below.

The correct dosage of Megaplat depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Megaplat side effects, there are can be others also. These have been listed below. Usually, these side effects of Megaplat go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Megaplat's effect is Severe during pregnancy and Severe for lactating mothers. Warnings related to Megaplat's effects on the liver, heart and kidney, if any, have been listed below.

Megaplat is not recommended if you suffer from certain medical conditions as it can have adverse effects. Arrhythmia are examples of such conditions. Other contraindications of Megaplat have been discussed in the sections ahead.

Additionally, Megaplat may also adversely react with other medicines. See below for a complete list.

You should also be aware that Megaplat is not safe while driving, and is not addiction.

Megaplat Benefits & Uses
Megaplat Dosage & How to Take
Megaplat Side Effects
Megaplat Related Warnings
Severe Interaction of Megaplat with Other Drugs
Megaplat Contraindications
Frequently asked Questions about Megaplat
Megaplat Interactions with Food and Alcohol

Megaplat Benefits & Uses

Megaplat is used to treat the following -

Main Benefits

Colorectal Cancer

Other Benefits

Pancreatic Cancer

Megaplat Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Megaplat Related Warnings

Is the use of Megaplat safe for pregnant women?

Pregnant women may get severe side effects after taking Megaplat. If you are pregnant, do not take Megaplat without a doctor's advice.

Severe
Is the use of Megaplat safe during breastfeeding?

Megaplat may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Megaplat on the Kidneys?

Very few cases of side effects of Megaplat on kidney have been reported.

Mild
What is the effect of Megaplat on the Liver?

Megaplat can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Megaplat on the Heart?

Megaplat can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate

Severe Interaction of Megaplat with Other Drugs

Megaplat should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amiodarone

Clozapine

Fentanyl

Etanercept

Haloperidol

Emtricitabine,Tenofovir,Efavirenz

Moderate

Aspirin

Azithromycin

Megaplat Contraindications

If you are suffering from any of the following diseases, you should not take Megaplat unless your doctor advises you to do so -

Heart Disease
Liver Disease
Neutropenia
Peripheral Neuropathy
Arrhythmia

Frequently asked Questions about Megaplat

Is this Megaplat habit forming or addictive?

Forming a habit of Megaplat has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Megaplat as you may feel sleepy.

Dangerous
Is it safe?

Yes, but consume Megaplat only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Megaplat is unable to treat or cure mental disorders.

No

Megaplat Interactions with Food and Alcohol

Interaction between Food and Megaplat

Taking Megaplat with food is safe.

Safe
Interaction between Alcohol and Megaplat

Consult your doctor before consuming alcohol while taking Megaplat as it can have severe side effects.

Severe

See all substitutes for Megaplat

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)

Megaplat