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Nikacin, a prescription drug, is manufactured in various forms such as Injection. It is primarily used for the treatment of Urinary Tract Infection. Nikacin also has some secondary and off-label uses. These are listed below.
Medical history of the patient along with age and gender determines the dosage of Nikacin. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.
Apart from the aforementioned side effects, Nikacin can also lead to other problems, which have been listed below. Such side effects of Nikacin normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Nikacin is Severe for pregnant women and Unknown for women who are breastfeeding. It is important to know if Nikacin has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Nikacin related warnings section.
Nikacin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Some other conditions that can be affected by Nikacin are listed in the contraindications section below.
Drug reaction of Nikacin with other medicines has been reported. See below for a complete list.
Along with the above-mentioned precautions, remember that taking Nikacin is considered safe while driving, and is addictive.
Nikacin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Is the use of Nikacin safe for pregnant women?
Nikacin should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.
Is the use of Nikacin safe during breastfeeding?
Due to lack of research work on this topic, the side effects of Nikacin for breastfeeding women are not known.
What is the effect of Nikacin on the Kidneys?
Nikacin may have severe effects on your kidney, so do not take it without consulting your doctor.
What is the effect of Nikacin on the Liver?
Nikacin has very mild side effects on the liver.
What is the effect of Nikacin on the Heart?
Nikacin may have mild side effects on the heart. Most people will never see any effect on the heart.
Nikacin should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Nikacin unless your doctor advises you to do so -
Is this Nikacin habit forming or addictive?
No, there is no any evidence that Nikacin is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Nikacin since it will not make you feel sleepy.
Is it safe?
Nikacin should be used only after doctor's advice.
Is it able to treat mental disorders?
Nikacin is unable to treat or cure mental disorders.
Interaction between Food and Nikacin
It is safe to take Nikacin with food.
Interaction between Alcohol and Nikacin
No research has been done on this till date. Therefore, it is not known what the effect of taking Nikacin with alcohol will be.
Do not self-administer Nikacin. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Nikacin please inform your doctor immediately.
Nikacin is a prescription drug, hence do not take Nikacin without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.
No, Nikacin cannot be taken with penicillin. Because penicillin inactivates the Nikacin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Nikacin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
Yes, Nikacin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.
Yes, Nikacin is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Nikacin taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Nikacin with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137