Oplatin Information

Oplatin is a prescription drug, available for use as Injection, Infusion. Colorectal Cancer are some of its major therapeutic uses. Secondary and off-label uses of Oplatin have also been mentioned below.

The correct dosage of Oplatin depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. For detailed information on this, read through the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Oplatin as well, which are listed below. Such side effects of Oplatin normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.

Oplatin's effect during pregnancy is Severe and Severe while nursing. Further, the section on Oplatin related warnings talks about Oplatin's effects on the liver, heart and kidney.

Oplatin is contraindicated in people with pre-existing medical conditions like Arrhythmia as it can result in adverse effects. The section on Oplatin contraindications lists all such conditions.

Drug interactions for Oplatin have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Oplatin, it is important to know that it is not safe while driving, and is not habit-forming.

Oplatin Benefits & Uses
Oplatin Dosage & How to Take
Oplatin Side Effects
Oplatin Related Warnings
Severe Interaction of Oplatin with Other Drugs
Oplatin Contraindications
Frequently asked Questions about Oplatin
Oplatin Interactions with Food and Alcohol

Oplatin Benefits & Uses

Oplatin is used to treat the following -

Other Benefits

Colorectal Cancer

Oplatin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Oplatin Related Warnings

Is the use of Oplatin safe for pregnant women?

Oplatin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Oplatin without medical advice.

Severe
Is the use of Oplatin safe during breastfeeding?

Women who are breastfeeding may experience severe harmful effects after taking Oplatin. It should only be taken after medical advice.

Severe
What is the effect of Oplatin on the Kidneys?

Oplatin may have mild side effects on the kidneys.

Mild
What is the effect of Oplatin on the Liver?

The liver can be affected by Oplatin. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Oplatin only after medical advice.

Moderate
What is the effect of Oplatin on the Heart?

The heart can be affected by Oplatin. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

Moderate

Severe Interaction of Oplatin with Other Drugs

Oplatin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amiodarone

Clozapine

Fentanyl

Etanercept

Haloperidol

Emtricitabine,Tenofovir,Efavirenz

Moderate

Aspirin

Azithromycin

Oplatin Contraindications

If you are suffering from any of the following diseases, you should not take Oplatin unless your doctor advises you to do so -

Heart Disease
Liver Disease
Neutropenia
Peripheral Neuropathy
Arrhythmia

Frequently asked Questions about Oplatin

Is this Oplatin habit forming or addictive?

Oplatin does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Oplatin, you should not drive or work on any heavy machine, as Oplatin can make you drowsy.

Dangerous
Is it safe?

Yes, but take Oplatin only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Oplatin is not used to treat mental disorders.

No

Oplatin Interactions with Food and Alcohol

Interaction between Food and Oplatin

Taking Oplatin with food does not harm your health.

Safe
Interaction between Alcohol and Oplatin

Consult your doctor before consuming alcohol while taking Oplatin as it can have severe side effects.

Severe

See all substitutes for Oplatin

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)

Oplatin