Oxitrust

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Oxitrust Information

Oxitrust is a prescription medicine that is available as a Injection. It is primarily used for the treatment of Colorectal Cancer. Other than this, Oxitrust has some other therapeutic uses, which have been discussed ahead.

The optimal dosage of Oxitrust is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Oxitrust as well, which are listed below. Normally, these side effects of Oxitrust are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Oxitrust has a Severe effect for pregnant women and Severe effect on lactating mothers. It is important to know if Oxitrust has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Oxitrust related warnings section.

Individuals suffering from medical conditions like Arrhythmia must refrain from the use of Oxitrust since this can cause severe adverse effects. Some other conditions that can be affected by Oxitrust are listed in the contraindications section below.

Besides this, Oxitrust may also have severe interaction with some medicines. See below for a complete list.

In addition to these precautions, you may also note that Oxitrust is not safe while driving, and is is not addictive in nature.



Oxitrust Benefits & Uses

Oxitrust is used to treat the following -

Other Benefits

Oxitrust Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Colorectal Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 140 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: 6 months
  • Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric
  • Disease: Colorectal Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 140 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: 6 months
  • Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Oxitrust Related Warnings

  • Is the use of Oxitrust safe for pregnant women?


    Oxitrust has many dangerous side effects in pregnant women. If you are pregnant, do not consume Oxitrust without medical advice.

    Severe
  • Is the use of Oxitrust safe during breastfeeding?


    Taking Oxitrust may lead to serious side effects if you are breastfeeding. Oxitrust should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Oxitrust on the Kidneys?


    Oxitrust may have mild side effects on the kidneys.

    Mild
  • What is the effect of Oxitrust on the Liver?


    The liver can be affected by Oxitrust. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Oxitrust only after medical advice.

    Moderate
  • What is the effect of Oxitrust on the Heart?


    There may be an adverse effect on the heart after taking Oxitrust. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

    Moderate


Severe Interaction of Oxitrust with Other Drugs

Oxitrust should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Oxitrust Contraindications

If you are suffering from any of the following diseases, you should not take Oxitrust unless your doctor advises you to do so -



Frequently asked Questions about Oxitrust

  • Is this Oxitrust habit forming or addictive?


    Oxitrust does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Oxitrust, you should not drive or work on any heavy machine, as Oxitrust can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, Oxitrust is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Oxitrust is not used to treat mental disorders.

    No

Oxitrust Interactions with Food and Alcohol

  • Interaction between Food and Oxitrust


    Taking Oxitrust with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Oxitrust


    Taking alcohol with Oxitrust can be dangerous.

    Severe


See all substitutes for Oxitrust


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)



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