Pepraz I

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  • Manufactured by: East West Pharma
  • Contains / Salt: Rabeprazole (20 mg) + Itopride (150 mg)

Pepraz I Information

Pepraz I is a prescription drug, available for use as Capsule. Acidity, Heartburn are some of its major therapeutic uses. Secondary and off-label uses of Pepraz I have also been mentioned below.

The correct dosage of Pepraz I depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Pepraz I are Headache, Dizziness, Diarrhoea. Such side effects of Pepraz I normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Pepraz I is Unknown for pregnant women and Unknown for women who are breastfeeding. It is important to know if Pepraz I has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Pepraz I related warnings section.

Individuals suffering from medical conditions like Diarrhea (Loose Motions) must refrain from the use of Pepraz I since this can cause severe adverse effects. The section on Pepraz I contraindications lists all such conditions.

Besides this, Pepraz I may also have severe interaction with some medicines. See below for a complete list.

In addition to the above precautions for Pepraz I, it is important to know that it is not safe while driving, and is not habit-forming.


Pepraz I Benefits & Uses

Pepraz I is used to treat the following -

Other Benefits

Pepraz I Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Capsule
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 8 weeks
  • Special Instructions: strength 20 mg rabeprazole and 150 mg itopride
Geriatric
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Capsule
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 8 weeks
  • Special Instructions: strength 20 mg rabeprazole and 150 mg itopride

Pepraz I Side Effects

Based on research, the following side effects have been observed when Pepraz I is used -

Common

Pepraz I Related Warnings

  • Is the use of Pepraz I safe for pregnant women?


    The effects of Pepraz I on pregnant women are unknown since no research has been done to ascertain it yet.

    Unknown
  • Is the use of Pepraz I safe during breastfeeding?


    There is no research available on the side effects of Pepraz I in breastfeeding women. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Pepraz I on the Kidneys?


    In the absence of any research, there are no known side effects of Pepraz I on kidneys.

    Unknown
  • What is the effect of Pepraz I on the Liver?


    So far, no research has been carried out on the effects of Pepraz I on the liver. So it is not known whether taking Pepraz I will affect the liver or not.

    Unknown
  • What is the effect of Pepraz I on the Heart?


    In the absence of any scientific study on the side effects of Pepraz I on the heart, information on safety of Pepraz I for the heart is unavailable.

    Unknown

Severe Interaction of Pepraz I with Other Drugs

Pepraz I should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Pepraz I Contraindications

If you are suffering from any of the following diseases, you should not take Pepraz I unless your doctor advises you to do so -


Frequently asked Questions about Pepraz I

  • Is this Pepraz I habit forming or addictive?


    Forming a habit of Pepraz I has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Pepraz I you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Pepraz I is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Pepraz I is unable to treat or cure mental disorders.

    No

Pepraz I Interactions with Food and Alcohol

  • Interaction between Food and Pepraz I


    You can take Pepraz I with food.

    Safe
  • Interaction between Alcohol and Pepraz I


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Pepraz I.

    Unknown

Frequently asked Questions about Pepraz I

Question over 6 years ago

Can Pepraz I cause allergy?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Pepraz I may cause allergy in rare instances. An allergic reaction might lead to swelling of the face, development of a rash, throat tightness and difficulty in breathing. If you develop any of these symptoms, talk to your doctor immediately. He may stop Pepraz I for a while and examine you properly. 

Question over 6 years ago

Is Pepraz I given with itopride?

Dr. Faisal Mukhtar MBBS, PG Dip, DNB , Ophthalmology

Yes, Pepraz I is given in combination with itopride. The combination is used for the management of gastro-esophageal reflux disorder (GERD). 

Question almost 7 years ago

Does Pepraz I cause high blood pressure?

Dr. Vinod Verma MBBS , Diabetology

No, Pepraz I doesn't cause high blood pressure. High blood pressure can be managed by losing some amount of weight, doing some kind of physical activity on a daily basis, eating a healthy diet, reducing sodium in the diet, limiting the amount of alcohol and caffeine, quitting smoking, and taking less stress. If your blood pressure doesn't get controlled, your doctor might start you on a hypertensive drug ( amlodipine, telmisartan etc). Please follow the instructions of your doctor completely. 

Question about 7 years ago

What is Pepraz I?

Dr. Yogesh Kumar MBBS , General Physician

Pepraz I is a brand name for rabeprazole. It belongs to a class of medications known as proton pump inhibitors. It is available in the form of a tablet, capsule, and injection. Pepraz I is used to alleviate the symptoms of gastroesophageal reflux disorder (GERD). GERD is a condition in which acid back-flows from the stomach to the esophagus (the tube which connects the stomach with throat) causing heartburn and injury to the esophagus. Pepraz I is used to prevent this damage. Pepraz I is also used to treat conditions like Zollinger Ellison syndrome (excessive acid is produced by the stomach). It is used for the treatment of ulcers (sores in the lining of stomach and intestine) and also used in combination with other antibiotics (such as amoxicillin and clarithromycin) to manage H.pylori infection.

Question almost 7 years ago

Does Pepraz I cause diarrhea?

Dr. Saurabh Dhamdhere MBBS , Orthopedics

Yes, Pepraz I use is associated with the development of diarrhea. This might be related to an infection caused by Clostridium difficile. If you experience severe diarrhea after consuming this medicine, inform the doctor right away without further delay. In addition, one must take a lot of electrolytes and fluids for preventing dehydration. Taking an anti-diarrheal medication may also help.


See all substitutes for Pepraz I


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Aciphex® (rabeprazole sodium)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 653

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1077-1078

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 667-668

KD Tripathi. Essentials of Medical Pharmacology. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 667-668

Package leaflet [Internet]: RABEPRAZOLE. Accord Healthcare Limited

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