Setraline

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Setraline Information

Setraline is a prescription medicine that is available as a Tablet. It is primarily used for the treatment of Depression, Fear. Setraline also has some secondary and off-label uses. These are listed below.

The right dosage of Setraline depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

While these are the most often observed Setraline side effects, there are can be others also. These have been listed below. Such side effects of Setraline normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

In addition, Setraline's effect is Moderate during pregnancy and Severe for lactating mothers. In addition, Setraline's effects on the liver, heart and kidney are discussed below in the Setraline related warnings section.

Setraline can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Setraline in conditions like Suicidal Tendency, Bipolar Disorder. Other conditions have been mentioned below in the Setraline contraindications section.

Additionally, Setraline may also adversely react with other medicines. See below for a complete list.

In addition to the above precautions for Setraline, it is important to know that it is not safe while driving, and is not habit-forming.



Setraline Benefits & Uses

Setraline is used to treat the following -

Main Benefits

Other Benefits

Setraline Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 50 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: PMS
  • Before or After Meal: After Meal
  • Single Maximum Dose: 50 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Given continuously or during the luteal phase only
Geriatric
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Setraline Related Warnings

  • Is the use of Setraline safe for pregnant women?


    Setraline can have harmful effects in pregnant women. If you experience any discomfort after using Setraline, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Setraline safe during breastfeeding?


    Setraline should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Setraline on the Kidneys?


    Setraline is completely safe for kidneys.

    Safe
  • What is the effect of Setraline on the Liver?


    Setraline is rarely harmful for the liver.

    Mild
  • What is the effect of Setraline on the Heart?


    Setraline may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Setraline with Other Drugs

Setraline should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Setraline Contraindications

If you are suffering from any of the following diseases, you should not take Setraline unless your doctor advises you to do so -



Frequently asked Questions about Setraline

  • Is this Setraline habit forming or addictive?


    Setraline is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Setraline as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but take Setraline only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, this Setraline works for mental disorders.

    Yes

Setraline Interactions with Food and Alcohol

  • Interaction between Food and Setraline


    You can take Setraline with food.

    Safe
  • Interaction between Alcohol and Setraline


    Taking Setraline with alcohol can have severely harmful effects on your health.

    Severe


Frequently asked Questions about Setraline

Question over 4 years ago

Does Setraline induce hair loss?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Rarely, Setraline causes hair loss. This is a reversible side effect of Setraline, the problem goes away after discontinuation of this drug. For partial hair loss, you are advised to use hair tonic and discuss with your doctor about a better treatment option for hair loss.

Question over 4 years ago

Does Setraline cause anxiety?

Dr. Ramraj Meena MBBS , General Physician

No, Setraline doesn't cause anxiety. In fact, it helps to alleviate the symptoms of social anxiety. Anxiety can be effectively managed by breathing deeply, practicing meditation, and not taking much stress. In case of severe anxiety please speak to your doctor.

Question about 5 years ago

How to take Setraline?

Dr. Bharat MBBS , General Physician

Setraline is available in the form of a tablet which is to be taken orally or by mouth. It can be taken with food or on an empty stomach. Your doctor will suggest a dosing regimen as per the severity of your condition. Setraline should be taken on the same time every day so that one doesn't skip the dose. It is important to follow the instructions of your doctor completely.

Question over 4 years ago

Can Setraline cause suicidal and self-inflicting thoughts?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Setraline has been reported to cause suicidal, self-inflicting and distorted thoughts. If you are experiencing disorientation and life-threatening thoughts after taking this drug, consult your doctor immediately without any further delay. 

Question about 5 years ago

Is it safe to take Setraline?

Dr. Kumawat Vijay Kumar MBBS , General Physician

Yes, Setraline is safe to use, if taken in prescribed amount and duration as directed by the doctor. However, there are known side effects such as drowsiness, dizziness, blurred vision, trouble urinating, constipation, and impotence. If you are experiencing any of the above do inform your doctor.



See all substitutes for Setraline


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zoloft (sertraline hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 461

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1132-1134

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