Amikater 500 Injection

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1 Injection in 1 Packet
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1 INJECTION 1 Packet ₹ 63
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Mikacin 500 mg Injection
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Amikater 500 Injection Information

Amikater 500 Injection is a prescription medicine that is available as a Injection. It is primarily used for the treatment of Urinary Tract Infection. Other than this, Amikater 500 Injection has some other therapeutic uses, which have been discussed ahead.

The optimal dosage of Amikater 500 Injection is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Amikater 500 Injection as well, which are listed below. Normally, these side effects of Amikater 500 Injection are not long lasting and go away when the treatment is finished. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Amikater 500 Injection is Severe for pregnant women and Unknown for women who are breastfeeding. Further, the section on Amikater 500 Injection related warnings talks about Amikater 500 Injection's effects on the liver, heart and kidney.

Amikater 500 Injection is contraindicated in people with pre-existing medical conditions like Dehydration, Parkinson's Disease, Hearing Loss as it can result in adverse effects. The section on Amikater 500 Injection contraindications lists all such conditions.

Drug interactions for Amikater 500 Injection have been reported in the medical literature. See below for a complete list.

In addition to the above precautions for Amikater 500 Injection, it is important to know that it is safe while driving, and is habit-forming.



Amikater 500 Injection Benefits & Uses

Amikater 500 Injection is used to treat the following -

Main Benefits

Other Benefits

Amikater 500 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amikater 500 Injection Related Warnings

  • Is the use of Amikater 500 Injection safe for pregnant women?


    Amikater shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Amikater 500 Injection safe during breastfeeding?


    Information about safety of Amikater for women who are breastfeeding is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Amikater 500 Injection on the Kidneys?


    There may be some severe side effects of Amikater on your kidney. Do not take it unless a doctor says so.

    Severe
  • What is the effect of Amikater 500 Injection on the Liver?


    Amikater may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Amikater 500 Injection on the Heart?


    Side effects of Amikater rarely affect the heart.

    Mild


Amikater 500 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Amikater 500 Injection unless your doctor advises you to do so -



Frequently asked Questions about Amikater 500 Injection

  • Is this Amikater 500 Injection habit forming or addictive?


    Amikater 500 Injection is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Amikater 500 Injection since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, but take Amikater 500 Injection only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Amikater 500 Injection is unable to treat or cure mental disorders.

    No

Amikater 500 Injection Interactions with Food and Alcohol

  • Interaction between Food and Amikater 500 Injection


    Taking Amikater 500 Injection with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Amikater 500 Injection


    Due to lack of research, there is no information about the side effects of taking Amikater 500 Injection with alcohol.

    Unknown


Frequently asked Questions about Amikater 500 Injection

Question over 5 years ago

What is Amikater?

Amikater is a brand name for amikacin. It is a prescription drug which belongs to the class of medication known as an aminoglycoside antibiotic. It is a broad spectrum antibiotic which is used for the treatment of bacterial infection such as bone, joint, skin, intra-abdominal, pneumonia, and respiratory tract infection. It is used for short-term treatment (7 - 10 days) of bacterial infection in different part of the body. It is also used for the treatment of neonatal sepsis when sensitivity testing indicates that other aminoglycosides cannot be used.

Question over 5 years ago

How does Amikater work?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Amikater is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.

Question about 5 years ago

How to take Amikater?

Dr. Abhijit MBBS , General Physician

Do not self-administer Amikater. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Amikater please inform your doctor immediately. 

Question almost 5 years ago

Can I take Amikater with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Amikater cannot be taken with penicillin. Because penicillin inactivates the Amikater by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amikater should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question almost 5 years ago

Does Amikater cause constipation?

Aakash Shah MBBS, MBBS , General Physician

No, Amikater does not cause constipation in patients who are taking it. However, if you are experiencing constipation after taking this drug then inform your doctor and take precautionary methods such as eating fibrous foods to avoid constipation.



See all substitutes for Amikater



This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience



References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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