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What is Calcium Deficiency?

99% of the calcium in our body is stored as hard tissue in form of teeth and bones.  It is a crucial nutrient which is necessary for critical body functions such as transmitting messages through nerves, hormone secretion, contraction and expansion of blood vessels and muscle, most importantly it supports skeletal function.

Calcium deficiency is also known as hypocalcaemia.  Untreated chronic hypocalcaemia raises severe concerns for complications like thinning of bones (osteopenia), weak bones in children (rickets) and excessive loss of bone density (osteoporosis).  The best part about a calcium deficiency is that it is curable by modifying dietary habits.

What are its signs and symptoms?

It is difficult to identify calcium deficiency at initial stages. However, certain symptoms can be noticed once the condition starts to progress.

Early symptoms include:

Chronic calcium deficiency can affect several other body parts. Late symptoms include:

  • Osteopenia and osteoporosis- proneness to fractures
  • Dental problems-dental and enamel hypoplasia, blunted tooth root development, and delay of tooth eruption.
  • Weak and brittle nails
  • Dry and itchy skin – eczema
  • Depression and Confusion
  • Poor appetite (Read more: Loss of appetite causes)
  • Abnormal heart rhythms (Read more: Arrhythmia prevention)
  • Delay in blood clotting

What are its causes?

Minimum requirement of calcium is 700 mg per day for an adult and 1200 mg per day for an elderly. 

Populations that are at a high risk for calcium deficiency are

Some of the most common causes of calcium deficiency are as follows:

  • Poor dietary intake
  • Malabsorption due to digestive disorders like celiac disease
  • Hypoparathyroidism
  • High and low levels of magnesium
  • High levels of phosphate
  • People on medicines like phenytoin, phenobarbital, rifampin, corticosteroids as well as chemotherapy drugs
  • Septic shock (Read more: Sepsis treatment)
  • Kidney failure
  • Pancreatitis
  • Low levels of vitamin D

How is it diagnosed and treated?

The physician first assesses the patients on the basis of clinical presentation and symptomatology. The next step to confirm clinical symptoms is to go for pathological testing which involves testing the levels of serum calcium, parathyroid hormone, serum phosphate, magnesium, 25-hydroxyvitamin D, and 1,25-dihydroxy vitamin D. The doctor might ask the individual to go for genetic mutation testing of the calcium-sensing receptor, the G protein subunit alpha 11.

Intake of calcium-rich diet not only treats hypocalcaemia but also prevents from having the condition in the first place. Rich sources of calcium are

  • Milk and other dairy products- cheese, yoghurt, curd and paneer
  • vegetables- spinach, broccoli, legumes- beans and peas
  • Fortified cereals, whole grains
  • Calcium-rich mineral water
  • Seafood, lean meats and eggs 
  • Nuts, seeds, soya products- tofu 

Calcium supplements prescribed by the physician can also help in improving calcium levels.

  • Avoid self-treatment
  • Avoid taking high doses of calcium – as doses are based on body weight. High doses can cause digoxin toxicity Remember, the calcium deficiency didn’t develop overnight and hence it will take time to recover.
  • Calcium supplements may interact with certain medications- blood pressure and cholesterol-lowering medicines, antibiotics- tetracyclines and fluoroquinolones.

Additionally, calcium injections may be required based on individual condition. It may take from one month to six months to completely treat hypocalcaemia depending upon the severity.

  1. Medicines for Calcium Deficiency
  2. Doctors for Calcium Deficiency
Dr. Tanmay Bharani

Dr. Tanmay Bharani

एंडोक्राइन ग्रंथियों और होर्मोनेस सम्बन्धी विज्ञान

Dr. Sunil Kumar Mishra

Dr. Sunil Kumar Mishra

एंडोक्राइन ग्रंथियों और होर्मोनेस सम्बन्धी विज्ञान

Dr. Parjeet Kaur

Dr. Parjeet Kaur

एंडोक्राइन ग्रंथियों और होर्मोनेस सम्बन्धी विज्ञान

Medicines for Calcium Deficiency

Medicines listed below are available for Calcium Deficiency. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
GemcalGEMCAL 120ML LIQUID126
CalcirolCalcirol 600000 IU Capsule165
RenolenRenolen Eye Drop47
Calcium + Calcitriol TabletCalcium 500 Mg + Calcitriol 0.25 Mg Tablet5
Calcitriol + Calcium Carbonate + ZincCalcium Carbonate 500 Mg + Calcitriol 0.25 Mcg + Zinc 7.5 Mg Tablet6
Calcium + Vitamin D3Calcium + Vitamin D3 250 IU Tablet4
Dailycal OKDAILYCAL OK TABLET 15S120
OsifortOSIFORT TABLET 30S0
DisprinDISPRIN 325MG TABLET 10S8
T ScoreT Score Kit0
CatlonCatlon Drop54
NelciumNelcium Injection40
SterofundinSterofundin Iso Infusion180
AlfacalcidolAlfacalcidol 0.25 Mcg Soft Gelatin Capsules15
Vitalpha CVitalpha C Tablet44
ResicaRESICA KIT 35/500MG/500IU TABLET 13S50
AuxitrolAuxitrol Capsule112
DevitaDevita 6 Lac Injection0
LaretolLaretol 1 Mcg Injection92
OstriolOstriol Capsule0
Ringer Lactate (Claris)Ringer Lactaten Infusion38
PsorafusePsorafuse 3 Mcg Cream289

Do you or anyone in your family have this disease? Please do a survey and help others

References

  1. Judith A. Beto. The Role of Calcium in Human Aging. Clin Nutr Res. 2015 Jan; 4(1): 1–8. PMID: 25713787
  2. Maoqing Wang. et al. Calcium-deficiency assessment and biomarker identification by an integrated urinary metabonomics analysis. BMC Med. 2013; 11: 86. PMID: 23537001
  3. Connie M. Weaver. et al. Calcium. Adv Nutr. 2011 May; 2(3): 290–292. PMID: 22332061
  4. Fujita T. Calcium paradox: consequences of calcium deficiency manifested by a wide variety of diseases.. J Bone Miner Metab. 2000;18(4):234-6. PMID: 10874605
  5. Diriba B. Kumssa. et al. Dietary calcium and zinc deficiency risks are decreasing but remain prevalent. Sci Rep. 2015; 5: 10974. PMID: 26098577
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