Amisafe

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1 INJECTION 1 Packet ₹ 15
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Amisafe Information

Amisafe is a prescription medicine that is available as a Injection. Urinary Tract Infection are some of its major therapeutic uses. Amisafe also has some secondary and off-label uses. These are listed below.

The right dosage of Amisafe depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Amisafe can also lead to other problems, which have been listed below. Normally, these side effects of Amisafe are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

In addition, Amisafe's effect is Severe during pregnancy and Unknown for lactating mothers. It is important to know if Amisafe has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Amisafe related warnings section.

Amisafe is contraindicated in people with pre-existing medical conditions like Dehydration, Parkinson's Disease, Hearing Loss as it can result in adverse effects. The section on Amisafe contraindications lists all such conditions.

Besides this, Amisafe may also have severe interaction with some medicines. Refer to the list below for further details.

In addition to these precautions, you may also note that Amisafe is safe while driving, and is is addictive in nature.



Amisafe Benefits & Uses

Amisafe is used to treat the following -

Main Benefits

Other Benefits

Amisafe Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amisafe Related Warnings

  • Is the use of Amisafe safe for pregnant women?


    Amisafe can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Amisafe safe during breastfeeding?


    There is no research available on the side effects of Amisafe in breastfeeding women. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Amisafe on the Kidneys?


    Amisafe may have severe effects on your kidney, so do not take it without consulting your doctor.

    Severe
  • What is the effect of Amisafe on the Liver?


    Amisafe may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Amisafe on the Heart?


    Side effects of Amisafe rarely affect the heart.

    Mild


Severe Interaction of Amisafe with Other Drugs

Amisafe should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Amisafe Contraindications

If you are suffering from any of the following diseases, you should not take Amisafe unless your doctor advises you to do so -



Frequently asked Questions about Amisafe

  • Is this Amisafe habit forming or addictive?


    Forming a habit of Amisafe has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Amisafe will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but consume Amisafe only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Amisafe in mental disorders is not effective.

    No

Amisafe Interactions with Food and Alcohol

  • Interaction between Food and Amisafe


    Taking Amisafe with food is safe.

    Safe
  • Interaction between Alcohol and Amisafe


    It is difficult to say anything about the effect of Amisafe and alcohol. No research has been done on this yet.

    Unknown


Frequently asked Questions about Amisafe

Question almost 5 years ago

Can I take Amisafe with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Amisafe cannot be taken with penicillin. Because penicillin inactivates the Amisafe by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amisafe should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question over 4 years ago

Is Amisafe available in tablet form?

Dr. Sangita Shah MBBS , General Physician

No, Amisafe is not available in tablet form. It is available in only injectable dosage form either given by intramuscularly or intravenously depends on patient condition or severity of infections. 

Question about 5 years ago

Can I take Amisafe with lidocaine?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Amisafe can be taken with lidocaine. The clinical report suggests that no harmful drug-drug interactions have been observed between them so far. However, it doesn't mean that no interaction could exist between them. These two medicines are high alert drug so you must consult your doctor before taking Amisafe together.

Question over 4 years ago

Does Amisafe cover pseudomonas?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Amisafe is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Amisafe will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.

Question almost 5 years ago

Does Amisafe cause diarrhea?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Amisafe has been reported to cause diarrhoea and it is a common side effect of this medicine. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after using this drug, discuss with your doctor immediately without any further delay. 



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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