Provalex

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Provalex Information

Provalex is a prescription medicine that is available as a Tablet. Primarily, it is used for the treatment of Epilepsy, Migraine. The alternative uses of Provalex have also been explained below.

Medical history of the patient along with age and gender determines the dosage of Provalex. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

While these are the most often observed Provalex side effects, there are can be others also. These have been listed below. These side effects of Provalex are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Provalex's effect during pregnancy is Severe and Mild while nursing. It is important to know if Provalex has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Provalex related warnings section.

Provalex is not recommended if you suffer from certain medical conditions as it can have adverse effects. Depression, Liver Disease are examples of such conditions. Other conditions have been mentioned below in the Provalex contraindications section.

Drug reaction of Provalex with other medicines has been reported. A complete list of these interactions is given below.

In addition to the above precautions for Provalex, it is important to know that it is not safe while driving, and is not habit-forming.



Provalex Benefits & Uses

Provalex is used to treat the following -

Main Benefits

Other Benefits

Provalex Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled.
13 - 18 years (Adolescent)
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled
Geriatric
  • Disease: Mania
  • Before or After Meal: After Meal
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: delayed-release tablet

Provalex Related Warnings

  • Is the use of Provalex safe for pregnant women?


    Provalex can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Provalex safe during breastfeeding?


    Provalex has been seen to have minimal side effects on breastfeeding women.

    Mild
  • What is the effect of Provalex on the Kidneys?


    Provalex has very mild side effects on the kidneys.

    Mild
  • What is the effect of Provalex on the Liver?


    Very few cases of side effects of Provalex on the liver have been reported.

    Mild
  • What is the effect of Provalex on the Heart?


    There are no any side effects of Provalex for the heart.

    Safe


Severe Interaction of Provalex with Other Drugs

Provalex should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Provalex Contraindications

If you are suffering from any of the following diseases, you should not take Provalex unless your doctor advises you to do so -



Frequently asked Questions about Provalex

  • Is this Provalex habit forming or addictive?


    No, you will not get addicted to Provalex.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Provalex can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Provalex only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, Provalex is useful in treating mental disorders.

    Yes

Provalex Interactions with Food and Alcohol

  • Interaction between Food and Provalex


    Taking Provalex with food does not harm your health.

    Safe
  • Interaction between Alcohol and Provalex


    Taking alcohol with Provalex can be dangerous.

    Severe


Frequently asked Questions about Provalex

Question about 5 years ago

How to take Provalex?

Dr. Yogesh Kumar MBBS , General Physician

Ideally, Provalex can be taken once or twice daily depends on the severity of disease or advice by the doctor. It has to be taken with food to avoid stomach upset. However, you are recommended to take it as per the doctor's instructions only.

Question over 4 years ago

Can Provalex cause constipation?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, Provalex can cause constipation. It is a common side effect of this drug. However, the exact cause behind constipation is not known. If you are experiencing severe constipation after taking this drug, then please consult your doctor and follow his/her instructions.

Question about 5 years ago

Can I take Provalex with tramadol?

Dr. Mayank Yadav MBBS , General Physician

Yes, you can take Provalex with tramadol only on your doctor's advice because taking these drugs together might cause increase the risk of side effects such as difficulty concentrating, drowsiness, and confusion.

Question over 5 years ago

What is Provalex?

Dr. Saurabh Shakya MBBS , General Physician

Provalex is a brand name for divalproex. It is a prescription drug that belongs to the class of drug called anti-epileptic drug, also known as an anticonvulsant and anti-seizure medication. It is used in the treatment of epilepsy (seizure). Provalex is also used to treat mania associated with bipolar disorder and to prevent episodes of migraine headache. 

Question almost 5 years ago

Can Provalex cause memory loss?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Provalex can cause reversible memory loss. All drugs that depress signaling in the CNS can cause reversible memory loss. If you experience memory loss after taking medicine, please consult your doctor immediately and follow his/her instructions.



See all substitutes for Provalex


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 418

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote (divalproex sodium)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote Er (divalproex sodium)



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