Refexine

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Refexine Information

Refexine is a commercial drug that is prescribed in the form of Syrup, Tablet. It is primarily used for the treatment of Ear Infection, Tonsillitis, Bronchitis. Secondary and off-label uses of Refexine have also been mentioned below.

Medical history of the patient along with age and gender determines the dosage of Refexine. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.

Some other side effects of Refexine have been listed ahead. Such side effects of Refexine normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Refexine is Safe for pregnant women and Safe for women who are breastfeeding. It is important to know if Refexine has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Refexine related warnings section.

Some other conditions that can be affected by Refexine are listed in the contraindications section below.

Besides this, Refexine may also have severe interaction with some medicines. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Refexine is not safe while driving, and is is not addictive in nature.



Refexine Benefits & Uses

Refexine is used to treat the following -

Other Benefits

Refexine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Ear Infection (Otitis Media)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 200 mg
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Ear Infection (Otitis Media)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 200 mg
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Ear Infection (Otitis Media)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 200 mg
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Ear Infection (Otitis Media)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 8 mg/kg
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Ear Infection (Otitis Media)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 8 mg/kg
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Refexine Related Warnings

  • Is the use of Refexine safe for pregnant women?


    Refexine is safe to take during pregnancy.

    Safe
  • Is the use of Refexine safe during breastfeeding?


    Breastfeeding women can safely use Refexine.

    Safe
  • What is the effect of Refexine on the Kidneys?


    Refexine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Refexine on the Liver?


    There are no any side effects of Refexine on the liver.

    Safe
  • What is the effect of Refexine on the Heart?


    Refexine is completely safe for the heart.

    Safe


Severe Interaction of Refexine with Other Drugs

Refexine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Refexine Contraindications

If you are suffering from any of the following diseases, you should not take Refexine unless your doctor advises you to do so -



Frequently asked Questions about Refexine

  • Is this Refexine habit forming or addictive?


    No, there is no any evidence that Refexine is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Refexine can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Refexine only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Refexine is unable to treat or cure mental disorders.

    No

Refexine Interactions with Food and Alcohol

  • Interaction between Food and Refexine


    Taking Refexine with food is safe.

    Safe
  • Interaction between Alcohol and Refexine


    No research has been done on this till date. Therefore, it is not known what the effect of taking Refexine with alcohol will be.

    Unknown


Frequently asked Questions about Refexine

Question about 5 years ago

Can I take Refexine without consulting a doctor?

Dr. Surender Kumar MBBS , General Physician

Refexine is a prescription drug so do not take it without consulting doctor. It can be harmful for people to take this medicine without a doctor's advice.

Question almost 5 years ago

Does Refexine treat typhoid fever?

Dr. Ram Saini MD, MBBS , General Physician

Yes Refexine is used to treat typhoid fever. It is second-line treatment for typhoid fever. If other antibiotics are resistant to salmonella typhi then this drug is found to be very effective to give symptomatic relief during typhoid. 

Question about 5 years ago

How to use Refexine?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Refexine can be taken orally or intravenously. Medicine should be ideally taken with food(a light meal). Take this medicine in the required quantity and duration as prescribed by your doctor. 

Question about 5 years ago

Does Refexine cause stomach upset?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, [medicine] can cause stomach upset if taken on an empty stomach. It is a common side effect of this drug. Please inform your doctor if you are experiencing severe stomach upset after taking this medicine.

Question over 5 years ago

How does Refexine works?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Refexine works by inhibiting the growth of bacterial cell wall which is essential for the growth of bacteria. Hence, in this way, it prevents us from bacterial infection.



See all substitutes for Refexine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 307-309

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 728

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Suprax® (cefixime)



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