Mexate

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  • Contains / Salt: Methotrexate (15 mg)
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Mexate Information



Mexate Benefits & Uses

Mexate is used to treat the following -

Other Benefits

Mexate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Mexate Side Effects

Based on research, the following side effects have been observed when Mexate is used -

Moderate

  • Stomatitis (Inflammation of the mouth)

Mild

Common

  • पेट दर्द

Mexate Related Warnings

  • Is the use of Mexate safe for pregnant women?


    Mexate should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Mexate safe during breastfeeding?


    Mexate should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Mexate on the Kidneys?


    Mexate can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Mexate on the Liver?


    The liver can be affected by Mexate. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Mexate only after medical advice.

    Moderate
  • What is the effect of Mexate on the Heart?


    Mexate is rarely harmful for the heart.

    Mild


Severe Interaction of Mexate with Other Drugs

Mexate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Mexate Contraindications

If you are suffering from any of the following diseases, you should not take Mexate unless your doctor advises you to do so -



Frequently asked Questions about Mexate

  • Is this Mexate habit forming or addictive?


    No, there is no any evidence that Mexate is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Mexate will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but consume Mexate only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Mexate in mental disorders is not effective.

    No

Mexate Interactions with Food and Alcohol

  • Interaction between Food and Mexate


    Due to the absence of research, it is difficult to say how Mexate and food will interact.

    Unknown
  • Interaction between Alcohol and Mexate


    Chances of side effects of drinking alcohol while taking Mexate are low. If you feel any adverse effects, please seek medical advice as soon as possible.

    Mild


Frequently asked Questions about Mexate

Question almost 5 years ago

Can I take Mexate without consulting a doctor?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

No, Mexate is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it can cause unpleasant side effects. Hence, the patient should seek doctors advice before taking this medication by himself or herself.

Question over 4 years ago

Does Mexate cause weight gain?

Dr. Chinmaya Bal MBBS , General Physician

No, Mexate does not cause weight changes (weight gain or loss). It has not been reported by the patients who are taking this drug. However, if you are experiencing any unusual weight changes then it might be due to some other medical condition and you are advised to discuss it with your doctor.

Question about 5 years ago

What is Mexate?

Dr. R.K Singh MBBS , Diabetology

Mexate is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question about 5 years ago

Can I discontinue Mexate on my own without doctors advice?

Dr. Abhijit MBBS , General Physician

No, Mexate should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

Question about 5 years ago

How to take Mexate?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

The dosage of this drug may vary depending on the diagnosis and the patient's medical condition. Take Mexate as advised by your doctor. Ideally, oral Mexate has to be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with bone marrow depression, and improper liver or kidney function.



See all substitutes for Mexate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834



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