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Cilastat is a prescription medicine that is available as a Injection. Secondary and off-label uses of Cilastat have also been mentioned below.
The optimal dosage of Cilastat is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.
While these are the most often observed Cilastat side effects, there are can be others also. These have been listed below. Usually, these side effects of Cilastat go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Cilastat is Moderate for pregnant women and Moderate for women who are breastfeeding. In addition, Cilastat's effects on the liver, heart and kidney are discussed below in the Cilastat related warnings section.
Cilastat is not recommended if you suffer from certain medical conditions as it can have adverse effects. Kidney Disease, Kidney Disease are examples of such conditions. The section on Cilastat contraindications lists all such conditions.
Drug interactions for Cilastat have been reported in the medical literature. Refer to the list below for further details.
Along with the above-mentioned precautions, remember that taking Cilastat is considered safe while driving, and is addictive.
Cilastat is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Adult |
|
Geriatric |
|
Infant (1 month to 2 years) |
|
Neonates (0 to 1 month) |
|
Based on research, the following side effects have been observed when Cilastat is used -
Severe
Moderate
Mild
Is the use of Cilastat safe for pregnant women?
Pregnant women may experience moderate side effects from Cilastat. It is best to stop taking Cilastat immediately and inform your doctor if you notice any discomfort.
Is the use of Cilastat safe during breastfeeding?
Cilastat may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Cilastat, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Cilastat.
What is the effect of Cilastat on the Kidneys?
There can be some harmful effects on your kidneys after taking Cilastat. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Cilastat on the Liver?
There may be an adverse effect on the liver after taking Cilastat. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Cilastat on the Heart?
Very few cases of side effects of Cilastat on the heart have been reported.
Cilastat should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Cilastat unless your doctor advises you to do so -
Is this Cilastat habit forming or addictive?
Forming a habit of Cilastat has not been reported.
Interaction between Food and Cilastat
Cilastat may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.
Interaction between Alcohol and Cilastat
Consult your doctor before consuming alcohol while taking Cilastat as it can have severe side effects.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Primaxin® (imipenem and cilastatin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 731
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 676-678