Nikacin

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  • Manufactured by: Zydus Cadila
  • Contains / Salt: Amikacin (500 mg)
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Nikacin Information

Nikacin, a prescription drug, is manufactured in various forms such as Injection. It is primarily used for the treatment of Urinary Tract Infection. Nikacin also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Nikacin. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

Apart from the aforementioned side effects, Nikacin can also lead to other problems, which have been listed below. Such side effects of Nikacin normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Nikacin is Severe for pregnant women and Unknown for women who are breastfeeding. It is important to know if Nikacin has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Nikacin related warnings section.

Nikacin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Some other conditions that can be affected by Nikacin are listed in the contraindications section below.

Drug reaction of Nikacin with other medicines has been reported. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Nikacin is considered safe while driving, and is addictive.



Nikacin Benefits & Uses

Nikacin is used to treat the following -

Main Benefits

Other Benefits

Nikacin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage

Nikacin Related Warnings

  • Is the use of Nikacin safe for pregnant women?


    Pregnant women may get severe side effects after taking Nikacin. If you are pregnant, do not take Nikacin without a doctor's advice.

    Severe
  • Is the use of Nikacin safe during breastfeeding?


    Due to lack of research work on this topic, the side effects of Nikacin for breastfeeding women are not known.

    Unknown
  • What is the effect of Nikacin on the Kidneys?


    Use of Nikacin may be dangerous for kidney. Do not use it without doctor advice.

    Severe
  • What is the effect of Nikacin on the Liver?


    Nikacin may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Nikacin on the Heart?


    Nikacin may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Nikacin with Other Drugs

Nikacin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Nikacin Contraindications

If you are suffering from any of the following diseases, you should not take Nikacin unless your doctor advises you to do so -



Frequently asked Questions about Nikacin

  • Is this Nikacin habit forming or addictive?


    Nikacin does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Nikacin since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Nikacin is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Nikacin for mental disorders.

    No

Nikacin Interactions with Food and Alcohol

  • Interaction between Food and Nikacin


    Taking Nikacin with food does not harm your health.

    Safe
  • Interaction between Alcohol and Nikacin


    No research has been done on this till date. Therefore, it is not known what the effect of taking Nikacin with alcohol will be.

    Unknown


Frequently asked Questions about Nikacin

Question about 5 years ago

How to take Nikacin?

Dr. Abhijit MBBS , General Physician

Do not self-administer Nikacin. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Nikacin please inform your doctor immediately. 

Question about 5 years ago

Can I take Nikacin without consulting a doctor?

Dr. Abhijit MBBS , General Physician

Nikacin is a prescription drug, hence do not take Nikacin without consulting doctor. It can be harmful to patients to take this medicine without a doctor's advice.

Question almost 5 years ago

Can I take Nikacin with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Nikacin cannot be taken with penicillin. Because penicillin inactivates the Nikacin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Nikacin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question over 4 years ago

Is Nikacin ototoxic?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Nikacin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.

Question almost 5 years ago

Is Nikacin nephrotoxic?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Nikacin is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Nikacin taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Nikacin with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137

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