myUpchar प्लस+ के साथ पूरेे परिवार के हेल्थ खर्च पर भारी बचत

What is diabetic ketoacidosis?

Diabetic ketoacidosis (DKA) is a complication of diabetes, which occurs as a result of abnormally high levels of ketones in the blood that make it acidic. It can lead to coma or death if left untreated. It is more common in type 1 diabetes and people with type 2 diabetes rarely suffer from DKA. There is limited information on the incidence of DKA in India

What are its main signs and symptoms?

Warning signs and symptoms of DKA include:

  • Excessive thirst
  • Frequent desire to pass urine (Read more: Frequent urination causes)
  • High blood sugar levels
  • High levels of ketone in the urine

Other symptoms that may appear include:

What are its main causes?

Lack of insulin in diabetes triggers the body to use fat as a source of energy. As fat is broken down, it results in the production of ketones. These excess ketones are then excreted in the urine.

DKA is mainly triggered by:

  • Infection: Presence of an illness can lead to an increase in the levels of certain hormones that nullify the action of insulin.
  • Insulin regimen: Improper or missed doses of insulin can cause DKA.
  • Inadequate food intake

Other factors include:

  • Emotional or physical trauma
  • Heart attack
  • Alcohol or drug abuse, typically cocaine
  • Medication use

How is it diagnosed and treated?

A medical history, physical examination and laboratory tests help a doctor to diagnose the condition. HbA1c and other blood sugar measurements are done. Ketones are primarily checked if the patient is a known case of diabetes. It can be done either by a urine or blood test. Other tests include:

  • Arterial blood gas measurement
  • Urine analysis
  • Osmolality blood test
  • Biochemical tests (tests for sodium, potassium, calcium, etc.)

The goal of treatment for DKA is blood sugar control. Oral blood sugar lowering agents may be given initially, or if your sugar level is too high, insulin may be preferred. The treatment is decided based on the sugar levels of the patient. Treatment also involves fluid and electrolyte replacement.

Self-care tips:

  • Carefully monitor blood sugar levels.
  • After taking anti-diabetic medicines, you may feel hypoglycemic. Keeping a sugar candy or chocolate with you can be helpful in case of emergency.
  • Take medicines as prescribed.
  • Check for ketones every 4-6 hours when you do not feel well.
  • Avoid exercising if your urine test shows presence of ketones.
  • If you feel uncomfortable or any of the warning symptoms occur, call your physician right away.

Lifestyle changes:

  • Restrict sugar-containing foods in the diet.
  • Choose foods low in fat and high in fibre.
  • Exercising is encouraged once the blood is free of ketones and sugar levels are under control.
  1. Medicines for Diabetic Ketoacidosis

Medicines for Diabetic Ketoacidosis

Medicines listed below are available for Diabetic Ketoacidosis. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
InsugenINSUGEN 30/70 40IU/10ML PFS INJECTION117
WosulinWOSULIN 30/70 100IU CARTRIDGE 3ML424
Lupisulin MLUPISULIN M 30 100IU INJECTION 10ML0
Insugen RINSUGEN R REFIL 100IU 3ML INJECTION780
MixtardHUMAN MIXTARD 100IU INJECTION328
NovorapidNOVORAPID FLEX PEN 3ML 100UNITS/ML INJECTION576
ActrapidACTRAPID FLEXPEN 100IU INJECTION 3ML471
Novomix 30 100 IuNovomix 30 100 Iu Flexpen537
HumalogHUMALOG 100IU CARTRIDGE INJECTION2712
Humalog MixHumalog 100 Iu/Ml Cartridge 3 Ml2040
Consegna RCONSEGNA R 200IU/3ML INJECTION264
RyzodegRYZODEG PENFILL 3ML 5S5875
Insucare MINSUCARE M30 40IU INJECTION 10ML119
InsucareINSUCARE 40IU INJECTION 10ML100
Eglucent kwikpenEGLUCENT KWIKPEN INJECTION 3ML619
Eglucent mixEGLUCENT MIX 25 CARTRIDGE 3ML542
Eglucent mix kwickpenEGLUCENT MIX 25 KWIKPEN INJECTION 3ML2712
HuminsulinHUMINSULIN 30/70 100IU INJECTION392
EglucentEGLUCENT 100IU RAPID CARTRIDGES 3ML542

Do you or anyone in your family have this disease? Please do a survey and help others

References

  1. British Medical Journal. Incidence and prevalence of diabetic ketoacidosis (DKA) among adults with type 1 diabetes mellitus (T1D): a systematic literature review. BMJ Publishing Group. [internet].
  2. American Diabetes Association. DKA (Ketoacidosis) & Ketones. Arlington, Virginia. [internet].
  3. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Diabetic ketoacidosis
  4. Tufts Medical Center. Diabetic Ketoacidosis Discharge Information. Massachusetts, United States. [internet].
  5. P. Hemachandra Reddy. Can Diabetes Be Controlled by Lifestyle Activities?. Curr Res Diabetes Obes J. 2017 Mar; 1(4): 555568. PMID: 29399663
और पढ़ें ...