Otisafe

Dr. Kishan Barnwal MBBS , General Physician

No, Otisafe does not cover Pseudomonas species. They are generally found to be resistant to Otisafe.

Dr. Sangita Shah MBBS , General Physician

Otisafe is bacteriostatic at the therapeutic dose that means it inhibits the growth of the bacteria but it can be bactericidal at higher doses. It works by inhibiting the protein synthesis in bacteria which it needs to survive. In the absence of protein synthesis, the bacterial growth is stunned and slowed.

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Yes, Otisafe can treat meningitis. It is a bacterial infection caused by Neisseria meningitidis that causes inflammation of the meninges around the brain and spinal cord. The duration of the treatment is usually 2 weeks.

Dr. Tarun kumar MBBS , Other

Yes, Otisafe may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discolouration of lips and skin. To avoid gray baby syndrome the doses of Otisafe must be lowered and adjusted as per the need.

Dr. Surender Kumar MBBS , General Physician

Yes, Otisafe can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.