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Due to poor lifestyle and health problems, many women face difficulty in conceiving. When a woman is unable to conceive naturally, then IVF (in vitro fertilization) can help her. IVF is such a process, which can help in giving happiness to couples facing infertility, but in some cases, IVF fails again and again. Many reasons can be responsible for IVF failure.

In this article, you will know in detail about the reasons for IVF failure -

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  1. Reasons for IVF failure
  2. How to reduce the risk of IVF failure?
  3. Takeaway
Doctors for IVF failure causes

There can be many reasons behind the failure of IVF, such as the woman's age or implantation problem, etc. All these reasons are mentioned below -

Old age

As women get older, the quality and quantity of their eggs start to decline. Because of this, the chances of women becoming pregnant are greatly reduced. Not only this, the decline in the quantity and quality of women's eggs can also affect IVF treatment. Because of this, pregnancy through IVF can be affected. According to health experts, women aged 35 years and above are more likely to fail IVF.

(Read More - IVF in India)

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Poor embryo quality

One of the main reasons for IVF not being successful can also be the quality of the embryo. In fact, during IVF treatment, a woman's egg and a man's sperm are mixed to create an embryo in the laboratory. Embryos may appear healthy in the laboratory, but when they are inserted into the uterus, they may fail for one reason or the other. Sometimes the embryos die instead of growing. Apart from this, sometimes due to some abnormality in the uterus, the fetus is not able to grow.

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Ovarian response

Sometimes a woman's ovaries don't respond to fertility drugs to produce eggs. At the beginning of IVF treatment, the woman is given an injection called follicle-stimulating hormone (FSH). This injection helps in increasing fertility and egg production, but some women's ovaries do not respond properly to this injection. Because of this, women fail to produce eggs.

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Implantation problem

In IVF treatment, egg and sperm are mixed. After this, it is inserted into the woman's uterus, but in some women, there is a problem in implantation, that is, the process of inserting the embryo into the uterus is not successful. Problems in implantation can come for many reasons. This includes -

  • Presence of polyps in the uterus.
  • Increase in progesterone hormone level.
  • Uterine infection.

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Bad lifestyle

As with a natural pregnancy, it is important to adopt a healthy lifestyle before and during IVF. The right lifestyle can help in conceiving. If a woman smokes, she should quit it a few months before starting IVF.

Smoking can affect fertility. Along with this, the weight of the woman should neither be less nor more while getting IVF done. During this, a healthy diet should be taken and exercise should be done regularly. Not only this, but during IVF women should also keep their distance from fast food, junk food, and alcohol.

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Differences in Chromosome

IVF can also fail due to embryos having chromosomal abnormalities. This means that the chromosomal DNA in the embryo is missing or is too much. Apart from this, an irregular part of the chromosome of the embryo can also cause IVF failure. In these situations, the body does not accept the embryo and IVF becomes unsuccessful.

The variation in the chromosome may be inherited from either parent or it may also develop during the early stages of embryonic division. According to health experts, there is a high possibility of chromosomal variation in the fetuses of women above 35 years of age.

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Active reproductive immunity

When a woman has overactive immune cells in her body, it can cause the IVF process to fail. If you are undergoing IVF but are unable to conceive, there is a high possibility that your immune cells are attacking the embryo.

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In some cases, IVF is successful in one go, but many times it is processed 2 or more times to make IVF successful. Not only this, many times even after doing IVF repeatedly, pregnancy does not happen, that is, IVF fails again and again. In such a situation, if you want to know about the reasons for IVF failure, then for this you can get some tests done first. This can significantly reduce the risk of recurrent IVF failure -

  • Immune test
  • Infection screening
  • Uterine cavity assessment
  • Karyotype test
  • Sperm assessment

(Read More - Pregnancy test kit)

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When a woman is unable to conceive naturally, then couples resort to IVF to become parents. In some cases, the IVF process becomes successful in one go, but in some cases, IVF fails repeatedly. IVF can be unsuccessful due to poor quality of egg and sperm, old age of the woman, poor lifestyle, and problems with implantation. In such a situation, the doctor can find out the reasons for this by examining you. After treating this reason, you can think of getting IVF done again.

(Read More - Pregnancy test before missed period)

Dr. Pratik Shikare

Dr. Pratik Shikare

Obstetrics & Gynaecology
5 Years of Experience

Dr. Payal Bajaj

Dr. Payal Bajaj

Obstetrics & Gynaecology
20 Years of Experience

Dr Amita

Dr Amita

Obstetrics & Gynaecology
3 Years of Experience

Dr. Sheetal Chandorkar

Dr. Sheetal Chandorkar

Obstetrics & Gynaecology
6 Years of Experience

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